- ￥168 - 1441
- TargetMol
- USA
- T1206
- 2025年07月13日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
2-8°C
- 保质期：
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -1248℃ for several months.
- 英文名：
Amsacrine
- 库存：
详询
- 供应商：
详询
- CAS号：
51264-14-3
- 规格：
2mg/10mg/50mg/100mg/1ml/10mM
| 规格： | 2mg | 产品价格： | ￥168.0 |
|---|---|---|---|
| 规格： | 10mg | 产品价格： | ￥437.0 |
| 规格： | 50mg | 产品价格： | ￥847.0 |
| 规格： | 100mg | 产品价格： | ￥1441.0 |
| 规格： | 1ml/10mM | 产品价格： | ￥685.0 |
ID：T1206
PURITY：0.99
Formula：C21H19N3O3S
MolWt：393.46
Appearance：桔红色粉末
Solubility：G4DMSO 25 mg/ml
Bioactivity：Aminoacridine derivative that is a potent intercalating antineoplastic agent. It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors. It is frequently used in combination with other antineoplastic agents in chemotherapy protocols. It produces consistent but acceptable myelosuppression and cardiotoxic effects.
Status：USAN, INN, BAN
Pathways：DNA Damage/DNA Repair
Target：Potassium Channel inhibitor; Topoisomerase inhibitor
Receptor：Potassium Channel;topoisomerase II
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文献和实验Drug-Induced Cytotoxicity in Tissue Culture
in a reversible reaction. However, treatment with numerous chemotherapeutic agents, including the epipodophyllotoxins, amsacrine and Adriamycin, stabilize the topo II-DNA complex with the DNA in the cleaved state (reviewed 1 ,2 ). The mechanisms by which complex
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