- ￥108 - 998
- TargetMol
- USA
- T0498
- 2025年07月16日
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- 详细信息
- 技术资料
- 保存条件：
RT
- 保质期：
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -530℃ for several months.
- 英文名：
Sasapyrine
- 库存：
详询
- 供应商：
详询
- CAS号：
552-94-3
- 规格：
2mg/10mg/50mg/200mg/1ml/10mM
| 规格： | 2mg | 产品价格： | ￥108.0 |
|---|---|---|---|
| 规格： | 10mg | 产品价格： | ￥248.0 |
| 规格： | 50mg | 产品价格： | ￥638.5 |
| 规格： | 200mg | 产品价格： | ￥998.0 |
| 规格： | 1ml/10mM | 产品价格： | ￥218.0 |
ID：T0498
PURITY：0.98
Formula：C14H10O5
MolWt：258.23
Appearance：白色粉末
Solubility：G4Soluble in DMSO
Bioactivity：Salsalate is a nonsteroidal anti-inflammatory agent for oral administration. Salsalate's mode of action as an anti-inflammatory and antirheumatic agent may be due to inhibition of synthesis and release of prostaglandins. The usefulness of salicylic acid, the active in vivo product of salsalate, in the treatment of arthritic disorders has been established. In contrast to aspirin, salsalate causes no greater fecal gastrointestinal blood loss than placebo. Salsalate is readily soluble in the small intestine where it is partially hydrolyzed to two molecules of salicylic acid. A significant portion of the parent compound is absorbed unchanged and undergoes rapid esterase hydrolysis in the body. The parent compound has an elimination half-life of about 1 hour. Salicylic acid (the active metabolite) biotransformation is saturated at anti-inflammatory doses of salsalate. Such capacity limited biotransformation results in an increase in the half-life of salicylic acid from 3.5 to 16 or more hours.
Status：USP, INN, BAN
Pathways：Neuroscience
Target：COX
Receptor：Prostaglandin G/H synthase 1/2
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