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- 文献和实验
- 技术资料
- 保存条件:
详询
- 保质期:
12 months from date of receipt.
- 英文名:
HIV-1 integrase inhibitor
- 库存:
99
- 供应商:
Biorbyt
- CAS号:
544467-07-4
- 规格:
100 mg/250 mg/1 g
| 规格: | 100 mg | 产品价格: | ¥8775.0 |
|---|---|---|---|
| 规格: | 250 mg | 产品价格: | ¥17082.0 |
| 规格: | 1 g | 产品价格: | ¥33579.0 |
描述: HIV-1 integrase inhibitor ((Z)-4-(3-(azidomethyl)phenyl)-2-hydroxy-4-oxobut-2-enoic acid) is uesful for anti-HIV.
分子式: C11H9N3O4
分子量: 247.2069
纯度: >98%
SMILES: OC(/C(O)=C/C(C1=CC=CC(CN=[N+]=[N-])=C1)=O)=O
研究领域: Infectious Disease & Virology; Pharmacology & Drug Discovery
备注: For research use only.
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文献和实验Assays for the Evaluation of HIV-1 Integrase Inhibitors
into the nucleus and integrated in the host chromosome. The only viral enzyme required for HIV-1 integration is integrase (IN), a protein of 32 kDa encoded by the 3′-end of the pol gene. The enzyme is produced by protease-mediated cleavage of the gag-pol precursor
Biochemical Screening Assays to Identify HIV-1 Integrase Inhibitors
Human immunodeficiency virus type 1 (HIV-1) integrase is, in addition to reverse transcriptase and protease, an important enzymatic target for antiretroviral drug development. Integrase plays a critical role in the HIV-1 life cycle
(PCR)-amplification and population, nucleotide sequencing (Sanger methodology) of a large part of the protease (PR), reverse transcriptase (RT), and integrase (IN) genes. In this chapter, we describe HIV-1 PR, RT, and IN genotyping on clinical samples
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