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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
零下80~20°C
- 保质期:
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名:
HIV-1 integrase inhibitor 4
- 库存:
10
- 供应商:
TargetMol
- CAS号:
1638504-66-1
- 规格:
50 mg/25 mg/100 mg
| 规格: | 50 mg | 产品价格: | ¥15300.0 |
|---|---|---|---|
| 规格: | 25 mg | 产品价格: | ¥11700.0 |
| 规格: | 100 mg | 产品价格: | ¥19500.0 |
Product Introduction
Bioactivity
英文名:HIV-1 integrase inhibitor 4
描述:HIV-1 integrase inhibitor 4 is an HIV-1 integrase strand transfer (INST) inhibitor (IC50: 3.7 nM).

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文献和实验Assays for the Evaluation of HIV-1 Integrase Inhibitors
into the nucleus and integrated in the host chromosome. The only viral enzyme required for HIV-1 integration is integrase (IN), a protein of 32 kDa encoded by the 3′-end of the pol gene. The enzyme is produced by protease-mediated cleavage of the gag-pol precursor
Biochemical Screening Assays to Identify HIV-1 Integrase Inhibitors
Human immunodeficiency virus type 1 (HIV-1) integrase is, in addition to reverse transcriptase and protease, an important enzymatic target for antiretroviral drug development. Integrase plays a critical role in the HIV-1 life cycle
A Conformationally Restricted -Strand HIV Protease Inhibitor
after the potent HIV protease inhibitor 2 , which together with a series of related derivatives was developed at Abbott Laboratories ( 11 ). This pseudopeptide contains a symmetrical diamino diol motif 8 (Fig. 2 ) flanked by Cbz-protected valine residues
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