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Unfolded Protein Binding: CALR, CANX, CCT4, DNAJB9, DNAJC10, ERO1LB, HSPA1B, HSPA2, HTRA2, PFDN5, PPIA, SCAP, SEC63, SIL1, TCP1, TOR1A, UGGT1.
ER Protein Folding Quality Control: EDEM1, GANAB, GANC, PRKCSH, RPN1, SERP1, ERP44, UGGT1.
Regulation of Cholesterol Metabolism: INSIG2, MBTPS1, MBTPS2, SCAP, SREBF1.
Regulation of Translation: EIF2A, EIF2AK3, PPP1R15A, SERP1.
ER Associated Degradation (ERAD): AMFR, DERL1, EDEM1, FBXO6, HERPUD1, HTRA2, HTRA4, MBTPS1, MBTPS2, NPLOC4, NUCB1, OS9, SEL1L, SELS, SYVN1, SEC62, UBXN4, VCP.
Ubiquitination: AMFR, HERPUD1, RNF5, SEL1L, SEC62, UBE2G2, UBXN4, UFD1L, USP14, VCP.
Transcription Factors: ATF4, ATF6, ATXN3, CALR, CEBPB, CREB3, CREB3L3, ATF6B, DDIT3, ERN1, ERN2, MBTPS1, PFDN5, SCAP, SREBF1, XBP1.
Protein Folding: CALR, CANX, CCT4, DNAJB9, DNAJC10, ERO1L, HSPA4L, PFDN5, PPIA, SEC63, SIL1, TCP1, TOR1A, ERP44, UGGT1.
Protein Disulfide Isomerization: DDIT3, DNAJC10, ERO1L, ERO1LB, PDIA3, SELS, SREBF1, ERP44.
Heat Shock Proteins: DNAJB9, DNAJC10, DNAJC3, HSPA4, HSPA5, HSPH1, SEC63.
Apoptosis: MANF, ATXN3, BAX, CALR, CEBPB, DDIT3, EIF2AK3, ERN1, ERN2, HSPA1B, HTRA2, MAPK8, MAPK9, PDIA3, PPP1R15A, SELS, VCP.
Pathway Activity Signature Genes: ADM2, ASNS, BEX2, DDIT3, DNAJB9, GINS2, HERPUD1, INHBE, KCNMB3, MCM4, PCNA, RRM2, SLC17A2, TRIB3, TYMS, UHRF1.
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文献和实验Analysis of Unfolded Protein Response in Arabidopsis
The unfolded protein response (UPR) is fundamental for development and adaption in eukaryotic cells. Arabidopsis has become one of the best model systems to uncover conserved mechanisms of the UPR in multicellular eukaryotes
Regulation of Apoptosis by the Unfolded Protein Response
, the cell has evolved highly specific signaling pathways collectively called the “unfolded protein response” (UPR) to restore normal ER functions. However, if the overload of unfolded or misfolded proteins in the ER is not resolved, the prolonged UPR
提供的PCR Array产品举例 订制的PCR芯片 如果现有的产品无法满足研究者的特定需要，SuperArray还可以提供从设计到芯片生产的完整服务，为研究者提供使用先进的PCR芯片的便捷服务。客户订制芯片服务为研究者提供以下便利：1）在使用表达谱基因组芯片后，对从基因组水平筛选出来的一组基因进行验证；2）在现有产品的基础上作适当调整以适应特殊需要；3）完全从头设计，适用于在现有的预设计PCR芯片中尚未包括的某个信号通路或者一组基因。若研究基因数目少于84个，还可以将96孔PCR芯片进一步分成
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