血管紧张素（1-7）拮抗剂A779

• 产品名称A 779，血管紧张素（1-7）拮抗剂A779
• 描述
  Selective angiotensin-(1-7) antagonist
• 生物学描述Selective angiotensin-(1-7) antagonist. Shows potent Mas receptor binding affinity (IC₅₀ = 0.3 nM). Antidiuretic and vasoconstrictor agent. Active in vivo and in vitro.
• 纯度> 93%

性能

• 分子量872.98
• 化学结构
• 分子式C₃₉H₆₀N₁₂O₁₁
• CAS编号159432-28-7
• 序列DRVYIHA (Modifications: Ala-7 = D-Ala)
• 存放说明Store at -20°C. Store under Desiccating conditions. The product can be stored for up to 12 months.
• 溶解度概述Soluble in water
• 处理

  A 779 (ab142820)参考文献

  This product has been referenced in:

• Xue H et al. Counteraction between angiotensin II and angiotensin-(1-7) via activating angiotensin type I and Mas receptor on rat renal mesangial cells. Regul Pept 177:12-20 (2012). Read more (PubMed: 22561449) »
• Maia LG et al. Angiotensin-(1-7) antagonist A-779 attenuates the potentiation of bradykinin by captopril in rats. J Cardiovasc Pharmacol 43:685-91 (2004). Read more (PubMed: 15071356) »
• Santos RA et al. Characterization of a new angiotensin antagonist selective for angiotensin-(1-7): evidence that the actions of angiotensin-(1-7) are mediated by specific angiotensin receptors. Brain Res Bull 35:293-8 (1994). Read more (PubMed: 7850477) »