Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood. LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearence of cholesterol from the circulation. In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36. Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described. MDA-treated LDL appear to be different from LDL oxidized by other means. This antibody reacts with MDA-treated LDL but not with native LDL.
克隆类型:
Mouse Monoclonal Antibody
亚型:
Mouse IgG2b/k
免疫原:
Low-density lipoprotein purified from human plasma and treated with malonyldialdehyde (MDA)
适用物种:
H
应用范围:
E, WB
应用说明:
Product Cat. No. 250412 reacts with MDA-treated LDL in ELISA and western blot. E: 1:20,000; WB: 1:1,000
别名:
low-density lipoprotein
形态:
Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
保存条件:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.