- ￥3000 - 6000
- 玉研仪器
- CHINA
- (ALZET Osmotic Pumps, Implantable Pumps，Alzet Osmotic Pumps
- 2026年01月31日
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- 详细信息
- 文献和实验
- 技术资料
- 国食药监械注册号：
无
- 库存：
100
- 供应商：
玉研科学仪器有限公司
- 现货状态：
现货供应,ALZET 动物微量给药渗透压泵
- 保修期：
12个月
ALZET 小动物缓释给药胶囊，也叫做渗透压微量给药胶囊泵 (ALZET Osmotic Pumps, Implantable Pumps，Alzet Osmotic Pumps）体积只有胶囊大小，可植入实验动物皮下或腹腔内或背部 , 直接或通过导管以 ul / 小时的速度持续准确地送出测试药剂，最长可达 6 个星期。
ALZET 小动物缓释给药胶囊有上万篇文献支持，操作方便，数据可靠。根据给药速度和给药量，有多种型号可选。
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ALZET微渗透压泵的优点 |
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Alzet Osmotic Pumps符合 USP 医疗用塑胶材料生物相容性标准，适合植入实验动物体內，针对特定部位給药，或將药剂用导管导入作用部位, 例如: 脊髓及颅腔内, 血管内, 肝脏, 脾脏及其它脏器肿瘤和创伤处。
Alzet Osmotic Pumps渗透压泵的技术参数:
AlZET脑输注附件套
ALZET微渗透压泵通过脑输注附件套，进行直接的脑部药物输注。已经有成百上千关于神经科学的文献发表，输注的药物包括生长因子，siRNA，精神药物等。
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文献和实验Basic fibroblast growth factor (FGF) promotes cartilage repair in vivo
... Alzet osmotic pumps delivering the mitogen to the site of injury promotes the healing of
intra-chondrial lesions by stimulating chondrocyte proliferation and the formation of extracellular matrix. ... Amer. J. Pathol., 81 (1975), pp. 337–346. Copyright © 1988 Published by Elsevier Inc. ...
An essential role for interferon gamma in resistance to Mycobac*terium tuberculosis infection.
... studies of murine IFN--y performed by Sharon Chen (Genentech, Inc., South San ... For continuous infusion, mice were subcutaneously implanted with osmotic pumps (Alza Corp., Palo Alto, CA...(B) gko mice were implanted subcutaneously with Alzet osmotic pumps loaded with IFN ...
The in‐vivo evaluation of an osmotic device (Osmet) using gamma scintigraphy
... 1 Alzet and Osmet are trademarks. ... DISCUSSION In the operation of the Osmet device, water is osmotically imbibed across the semipermeable mem- brane, swelling the osmotic
compartment and squeezing the drug reservoir uniformly along the axis. ...
… induced cell proliferation in rodent liver and kidney: a comparison of 5-bromo-2′-deoxyuridine and [3H] thymidine administered by injection or osmotic pump
... 2 h pulse 3 day pump 6 day pump 3 day pump; 3 weeks0 ... approximately 9 am, a second set of animals were implanted with pumps to deliver label for 3 days (Alzet models 1003D ... Product specifications state that osmotic pumps begin continuous delivery — 4 h after implantation. ...
Oral controlled‐release delivery of ivermectin in cattle via an osmotic pump
... Drug Delivery Device-Ivermectin was administered as a micel- lar solution contained within an ALZET 2ML4 mini-osmotic pump (ALZA Corp., Palo Alto ... The osmotic pumps were filled with the appropriate concen- tration of ivermectin solution to ensure that the defined dose ...
Osmotic drug delivery: a review of the patent literature
G Santus, RW Baker - Journal of Controlled Release, 1995 - Elsevier
... Water is drawn by osmosis into the salt chamber through semipermeable membrane. ... Coating containing solid osmotic compound ... Small pumps of this form are sold under the trade name Alzet® and are frequently used as implantable controlled-release delivery systems in ...
The impact of co-solvents and the composition of experimental formulations on the pump rate of the ALZET® osmotic pump
... the aqueous sodium chloride solution was needed for the initiation of the pumping and was ...facilitating the screen of lipophilic, poorly water-soluble compounds in osmotic pump studies ... ALZET,1992; ALZET Osmotic Pumps, Technical Information Manual, ALZA Corporation, 1992 ...
Identification of sulfated oligosaccharide-based inhibitors of tumor growth and metastasis using novel in vitro assays for angiogenesis and heparanase activity
... 88 was continually administered to the animals by ip-inserted 14-day Alzet mini-osmotic ... Detected by phycoerythrin-coupled rabbit F(ab′) 2 antimouse immunoglobulin (DAKO Corp., Carpinteria, CA ... at a dose of 20 mg/kg/day via ip 7-day mini-osmotic pumps (Alza Corporation). ...
Correlation of iron and zinc levels with lesion depth in newly formed atherosclerotic lesions
... Six weeks into the high cholesterol diet, two groups were treated with the iron chelating agent desferrioxamine, for 2 weeks and 4 weeks, respectively, by surgically implanting with Alzet osmotic pumps (Alza Corporation, Palo Alto, CA, USA) containing desferal (0.5 g/ml). ...
我国药物的剂型，从夏禹时代的酒曲、商代的汤剂到后来的丸散膏丹，已有四千余年的历史，近代又出现了片剂、冲剂、针剂、气雾剂等。 然而，这些常规剂型，不论口服或注射，每天大多需给药多次，不仅使用不便，而且血液中的药物浓度（简称血药浓度）起伏很大，导致“峰谷”现象。当药物浓度处于高峰时，超过了最适宜的治疗浓度，便引起较多副反应，甚至中毒；反之，药物浓度降到低谷时，又远在所需浓度之下，难以发挥作用。于是，新的药物剂型——缓释制剂与控释制剂也就相继应运而生了。它们均能控制药物释放速度，减少
肤组织有比较大的刺激性。如果一定要用皮下注射的方式可以考虑制备成微粒，比如脂质体，微球等，能够减小刺激性但可控性不是很好。三、顺铂用于肺癌裸鼠的给药方法1、顺铂小鼠给药的剂量为25mg/kg，通常将顺铂用生理盐水配成浓度为2.5mg/ml的溶液，按0.1ml/10g，腹腔注射。隔日给药一次。根据实验所用瘤株，给药时间长短也有不同。2、顺铂4mg/kg， 生理盐水配制，裸鼠，腹腔给药，0.2ml/10g体重，每5日给一次，可给3～4次。3、顺铂2mg/kg，裸鼠，腹腔给药，间日给。大约2周左右。4、若给裸鼠
目录 1、缓、控、速释制剂技术——固体、液体及复方 具有控制药物释放速度的缓、控、速释制剂技术，包括：透皮吸收制剂技术；注射缓、控释制剂(长效储库型注射剂)技术；口服（含舌下）缓、控、速释制剂技术；缓释微丸胶囊(直径为5～250μm)制剂技术；粘膜、腔道、眼用等其它缓、控释制剂技术等。 2、靶向给药系统 采用脂类、类脂蛋白质及生物降解高分子成分作为载体，将药物包封或嵌构而成的各种类型的新型靶向给药系统，包括：结肠靶向给药（口服）系统及技术；心脑靶向给药（口服、注射
技术资料