- ￥9300
- GeneTex
- 美国
- GTX75391
- 2025年07月09日
- IHC-P
- Mouse
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Prokaryotic recombinant protein corresponding to the external domain of the CD16 molecule, common to both the transmembrane form and the GPI-linked form.
- 亚型：
IgG2a
- 形态：
Liquid
- 保存条件：
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human
- 保质期：
12 months from the shipping date of the product.
- 抗原来源：
Human
- 目录编号：
GTX75391
- 级别：
Primary Antibodies
- 库存：
Available
- 供应商：
GeneTex
- 宿主：
Mouse
- 应用范围：
IHC-P
- 浓度：
>18 μg/ml (Please refer to the vial label for the specific concentration.)
- 靶点：
CD16
- 抗体英文名：
CD16 antibody [2H7]
- 抗体名：
CD16 抗体 [2H7]
- 规格：
500 μl
IHC-P analysis of human colon, ulcerative colitis tissue using GTX75391 CD16 antibody [2H7]. Note intense membrane staining of infiltrating natural killer cells, granulocytes and activated macrophages.
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文献和实验HIV-1-Specific Antibody-Dependent Cellular Cytotoxicity (ADCC)
-1-infected cells thereby decreasing viral load (1 –5 ) . The effector cells for ADCC are natural killer (NK) cells, that mediate lysis in a non-MHC restricted fashion. NK cells expressing CD16+ low affinity Fc-receptors bind to antibody which specifically
Methods for Measuring Antibody-Dependent Cell-Mediated Cytotoxicity In Vitro
Antibody-dependent cell-mediated cytotoxicity (ADCC) is a relevant characteristic to measure for a number of therapeutic monoclonal antibodies (mAbs) under development. ADCC is a mechanism by which antibody-opsonized, infected, or cancerous
到的细胞类型表达FcR，同时反应抗体含有Fc段，都应该考虑进行Fc 阻断，来确保实验的特异性，减少非特异的产生。 那么，具体哪些细胞类型需要做Fc阻断？ 首先，按FcR所结合的Ig种类不同可将其分为五类，即IgG（FcγR）、IgE（FcεR）、IgA（FcαR）、IgM（FcμR）和IgD（FcδR）。 IgG类型抗体的Fc受体是FcγR，依据和Fc片段亲和力的强弱，FcγR又可以被分为三个亚家族：FcγRI（CD64）、FcγRII（CD32）和FcγRIII（CD16）以及进一步还可以分为不同
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