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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthetic 19 amino acid peptide from C-terminus of human CHRM3 / M3.
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- 克隆性:
Polyclonal
- 标记物:
Unconjugated
- 适应物种:
Human,Monkey
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Human
- 目录编号:
GTX71587
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
GeneTex
- 宿主:
Rabbit
- 应用范围:
IHC-P
- 浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
- 靶点:
mAChR M3
- 抗体英文名:
mAChR M3 antibody
- 抗体名:
mAChR M3 抗体
- 规格:
25 μg
IHC-P analysis of human ovary, carcinoma tissue using GTX71587 mAChR M3 antibody.
Antigen retrieval : Heat-induced antigen retrieval
IHC-P analysis of human brain, glioblastoma tissue using GTX71587 mAChR M3 antibody.
Antigen retrieval : Heat-induced antigen retrieval
IHC-P analysis of human heart tissue using GTX71587 mAChR M3 antibody.
Antigen retrieval : Heat-induced antigen retrieval
IHC-P analysis of brain, alzheimer's disease neurofibrillary tangle tissue using GTX71587 mAChR M3 antibody.
IHC-P analysis of brain, glioblastoma tissue using GTX71587 mAChR M3 antibody.
IHC-P analysis of human brain, neurons and glia tissue using GTX71587 mAChR M3 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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文献和实验的。 研究发现,激活 M1 型毒蕈碱乙酰胆碱受体 (M1 mAChR) 可带来多重保护: • 通过 PKC 和 ERK1/2 通路,促进 APP 的非淀粉样切割 (激活 α-分泌酶,抑制 BACE); • 通过抑制 GSK3β,减少 tau 过度磷酸化; • 缺失 M1 则会加剧 Aβ/tau 病理与认知缺陷[10]。 ——这提示我们:增强胆碱能信号,或可同时阻断 Aβ 生成与 tau 病变,是极具潜力的治疗策略。 图 8. M1 mAChR 调控 AD 中淀粉样蛋白的生成过程[10
Important in phagocytosis via receptor-mediated endocytosis of IgG-antigen complexes Mediates antigen capture for presentation to T cells, antibody-dependent cellular cytotoxicity, release of cytokines and reactive oxygen intermediates Positive
Metabolic Labeling and Immunoprecipitation of Drosophila Proteins
Table of Contents Basic Protocol 1: Labeling and Immunoprecipitation of Proteins from Drosophila S2M3 Cells Support Protocol 1: Growth and Maintenance
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