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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Peptide (C)RIGLLGHPPHMNVNPQQPA, corresponding to amino acid residues 2732-2750 (Intracellular, C-terminus) of rat IP3R1 (Accession : P29994).
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- 克隆性:
Polyclonal
- 标记物:
Unconjugated
- 适应物种:
Human, Mouse, Rat
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Rat
- 目录编号:
GTX54759
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
GeneTex
- 宿主:
Rabbit
- 应用范围:
WB, ICC/IF, IHC-P, IP
- 浓度:
0.3 mg/ml (Please refer to the vial label for the specific concentration.)
- 靶点:
IP3 Receptor I
- 抗体英文名:
IP3 Receptor I antibody
- 抗体名:
IP3 Receptor I 抗体
- 规格:
50 μl
WB analysis of rat brain membrane lysate using GTX54759 IP3 Receptor I antibody preincubated with or without immunogen peptide.
Dilution : 1:2000
IHC-P analysis of mouse cerebellum tissue using GTX54759 IP3 Receptor I antibody. Immunoreactivity appears in Purkinje cells (arrows in A) and their dendritic trees. In addition, axonal processes coursing through cerebellar white matter are visualized (arrow in B).
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文献和实验IP3受体是一种内质网通道蛋白, 由四个相对分子质量为260kDa的糖蛋白组成的四聚体。四个亚基组成一个跨膜的通道, 每个亚基都有IP3结合的部位, 当3~4个部位被IP3占据时, 受体复合物构象发生改变, 打开离子通道, 储藏在内质网中的Ca2 随即释放,进入胞质溶胶。
Aspects of CNS Lupus: Mouse Models of Anti-NMDA Receptor Antibody Mediated Reactivity
This chapter describes methods utilized in establishing a mouse model of neuropsychiatric lupus encompassing both cognitive and emotional dysfunction, and a model of the influence of maternal antibody on the developing brain. The antibody
Single-Cell Imaging Techniques for the Real-Time Detection of IP3 in Live Cells
Inositol 1,4,5-trisphosphate (IP3 ) is a ubiquitous second messenger, derived from the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2 ) by enzymes of the phospholipase C (PLC) family. Binding of IP3 to its cognate receptor
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