- ￥5000
- GeneTex
- 美国
- GTX12257
- 2025年07月06日
- WB, ICC/IF, IP, IHC
- Rabbit
- Human, Mouse, Rat, Bovine
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
A 14-residue synthetic peptide corresponding to residues 4-17 of human PKG 1 beta. Tryptophan was substituted for tyrosine at position 9. A terminal cysteine was added and the peptide conjugated to KLH.
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- 克隆性：
Polyclonal
- 标记物：
Unconjugated
- 适应物种：
Human, Mouse, Rat, Bovine
- 保质期：
12 months from the shipping date of the product.
- 抗原来源：
Human
- 目录编号：
GTX12257
- 级别：
Primary Antibodies
- 库存：
Available
- 供应商：
GeneTex
- 宿主：
Rabbit
- 应用范围：
WB, ICC/IF, IP, IHC
- 浓度：
0.8 mg/ml (Please refer to the vial label for the specific concentration.)
- 靶点：
This antibody recognizes a protein corresponding to the molecular mass of the PKG 1? isoform.
- 抗体英文名：
PKG antibody
- 抗体名：
PKG 抗体
- 规格：
50 μg
Western blot analysis of GTX12257
Lane 1: MW marker
Lane 2: HeLa cell lysate
Lane 3: Rat brain tissue extract
Lane 4: MDBK cell lysate.
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文献和实验Lan T et al., J Ethnopharmacol 2020 (PMID:32526339)
Approaches for Monitoring PKG1 Oxidative Activation
cGMP-dependent protein kinase, also known as protein kinase G (PKG), is activated independently of cGMP by a novel thiol-reactive mechanism involving the formation of an intermolecular disulfide. This oxidative modification within PKG
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
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