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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
The immunogen recognized by this antibody maps to a region between residue 700 and 750 of human DNA-Methyltranserase 1 using the numbering given in entry NP_001370.1 (GeneID 1786).
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
- 克隆性:
Polyclonal
- 标记物:
Unconjugated
- 适应物种:
Human, Mouse
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Human
- 目录编号:
GTX11891
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
GeneTex
- 宿主:
Rabbit
- 应用范围:
WB, IP, PLA
- 浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
- 靶点:
DNMT1
- 抗体英文名:
DNMT1 antibody
- 抗体名:
DNMT1 抗体
- 规格:
50 μg
(A)WB analysis of HeLa nuclear extracts using GTX11891 DNMT1 antibody.
Loading amount : 50μg
(B)IP analysis of HeLa nuclear extracts using GTX11891 DNMT1 antibody.
Dilution : 0.2 μg/ml
WB analysis of HeLa and 293T cell lysate using GTX11891 DNMT1 antibody.
Dilution : 1 μg/ml
PLA analysis of MCF-7 cells using GTX11891 DNMT1 antibody and anti-human USP7 antibody.
Green : Actin
Red : positive signal
Blue : DAPI
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文献和实验A method for purification, identification and validation of DNMT1 mRNA binding proteins
DNA methyltransferase 1 (DNMT1) is the enzyme responsible for the maintenance of DNA methylation patterns during cell division. DNMT1 expression is tightly regulated within the cell cycle. Our previous study showed that the binding of a protein
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
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