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- 文献和实验
- 技术资料
- 免疫原:
A synthetic peptide corresponding to a sequence in the middle region of rat IL-13(80-102aa CNAIHRTQRILNGLCNQKASDVA).
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- 克隆性:
Polyclonal
- 标记物:
Unconjugated
- 适应物种:
Rat
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Rat
- 目录编号:
GTX11712
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
GeneTex
- 宿主:
Rabbit
- 应用范围:
WB
- 浓度:
500 μg/ml (Please refer to the vial label for the specific concentration.)
- 靶点:
IL13
- 抗体英文名:
IL13 antibody
- 抗体名:
IL13 抗体
- 规格:
100 μg
WB analysis of various samples using GTX11712 IL13 antibody.
Lane 1 : Recombinant rat IL-13 protein 5ng
Lane 2 : Recombinant rat IL-13 protein 2.5ng
Dilution : 0.5 μg/mL
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文献和实验做哮喘动物模型这些年,AAV-IL13是我见过最高效便捷的一种
酸性粒细胞(Eosinophils)和中性粒细胞(Neutrophils)的增加最为剧烈,淋巴细胞也有一定程度增加;同时,嗜酸性粒细胞关键趋化因子Ccl11(Eotaxin-1)在肺部呈现剂量依赖性上调。 杯状细胞化生与黏液分泌增加 肺组织PAS染色(糖原染色)显示,AAV-IL13处理的小鼠气道上皮发生强烈的杯状细胞化生(Goblet cell metaplasia)和黏液过度分泌,高剂量下甚至引发严重的黏液栓塞;粘蛋白基因Muc5ac的表达量显著上调。 2、群转录组特征
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
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