Recombinant Mouse LDLR / LDL Receptor Protein (His Tag) | 重组小鼠 LDLR / LDL Receptor 蛋白 (His标签)
- ￥2010 - 13070
- Sino Biological
- 北京
- 50305-M08H
- 2025年08月12日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
在-20℃ to -80℃
- 保质期：
12个月
- 英文名：
Recombinant Mouse LDLR / LDL Receptor Protein (His Tag)
- 库存：
99
- 供应商：
北京义翘神州科技股份有限公司
- 规格：
50 µg/500 µg
| 规格： | 50 µg | 产品价格： | ￥2010 |
|---|---|---|---|
| 规格： | 500 µg | 产品价格： | ￥13070 |
蛋白名称：LDLR/LDL Receptor蛋白, LDLR/LDL Receptor protein
蛋白构建：A DNA sequence encoding the extracellular domain of mouse LDLR (NP_034830.2) precursor (Met 1-Arg 790) with substitution of Val 23 and Gly 27 by Ala 23 and Cys 27 respectively was expressed with a C-terminal polyhistidine tag.
表达宿主：HEK293 Cells
蛋白纯度：> 90 % as determined by SDS-PAGE
蛋白活性：Measured by its binding ability in a functional ELISA. Immobilized Rat PCSK9 at 10 μg/ml (100 μl/well) can bind biotinylated recombinant mouse LDLR . The EC50 of biotinylated mouse LDLR is 0.173 μg/ml.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Ala 22
蛋白分子量：The secreted recombinant mouse LDLR comprises 780 amino acids with a predicted molecular mass of 85.7 kDa. As a result of glycosylation, it migarates as approximately 120-130 kDa protein in SDS-PAGE under reducing conditions.
蛋白NP号：NP_034830.2
蛋白氨基酸序列：Met1-Arg790
蛋白标签：C-His
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验2, Jacquot, G; et al. Optimization and in Vivo Validation of Peptide Vectors Targeting the LDL Receptor. Mol. Pharm., Pubmed: 27656777
3, Basak, JM; et al. Low-density lipoprotein receptor represents an apolipoprotein E-independent pathway of Aβ uptake and degradation by astrocytes. J. Biol. Chem., Pubmed: 22383525
4, Basak, JM. Modulating Amyloid Beta Clearance by Altering Cellular and Whole Brain Apolipoprotein E Metabolism. Thesis
.7. Wang, X. et al. 2011. Study of two G-protein coupled receptor variants of human trace amine-associated receptor 5. Sci Rep1: 102 (DOI:10.1038/srep00102).8. Wang, X. and Zhang, S. 2011. Production of a bioengineered G-protein coupled receptor of human
Mouse Strains and Genetic Nomenclature
., and Montagutelli, X. 2009. Genetic analysis of skull shape variation and morphological integration in the mouse using interspecific recombinant congenic strains between C57BL/6 and mice of the Mus spretus species. Evolution 63:2668‐2686
-sachs disease) IL2RGbase - Human IL2RG (Interleukin-2 receptor gamma) mutation db (X-SCID) L1CAM mutation - Human L1CAM mutation db LDLR mutation - Human LDLR mutation db (Familial hypercholesterolemia) LQTSdb - Long QT
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