Growth Hormone Receptor 蛋白|Growth Hormone Receptor protein|Growth Hormone Receptor(Mouse, His & Fc Tag)

小鼠 Growth Hormone Receptor蛋白|Growth Hormone Receptor protein|Growth Hormone Receptor(Mouse, C-human IgG1-Fc & His)（产品说明）
蛋白名称：Growth Hormone Receptor蛋白, Growth Hormone Receptor protein
蛋白构建：A DNA sequence encoding the extracellular domain (Met 1-Gln 273) of mouse GHR (NP_034414.2) precursor was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
表达宿主：HEK293 Cells
蛋白纯度：> 85 % as determined by SDS-PAGE
蛋白活性：Measured by its ability to inhibit proliferation of INS-1 cells induced by human growth hormone. The ED50 for this effect is 0.5-2 μg/mL in the presence of 50 ng/mL human growth hormone.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Thr 25
蛋白分子量：The recombinant mouse GHR/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer consists of 497 amino acids and has a predicted molecular mass of 56.8 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmGHR/Fc monomer is approximately 70-80 kDa due to glycosylation.
蛋白NP号：NP_034414.2
蛋白氨基酸序列：Met1-Gln273
蛋白标签：C-human IgG1-Fc & His
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.