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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD-19.
- 亚型:
Rabbit Ig
- 形态:
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1% BSA and 0.02% gentamicin. Antibody was purified by Protein-G affinity chromatography.
- 保存条件:
Store at -20°C.
- 克隆性:
多克隆
- 标记物:
见下方详细说明
- 适应物种:
H, M, R
- 保质期:
1-2年
- 抗原来源:
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD-19.
- 目录编号:
252248
- 级别:
超纯
- 库存:
大量
- 供应商:
Abbiotec
- 宿主:
Rabbit
- 应用范围:
E, WB, IHC
- 浓度:
见详细说明信息
- 靶点:
CD19
- 抗体英文名:
CD19 Antibody
- 抗体名:
CD19 Antibody
- 规格:
0.1 mg
CD19 Antibody产品详细介绍:
| 产品名称: | CD19 Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 252248 |
| 规格: | 0.1 mg |
| 产品描述: | CD19 is a 95 kDa type-I transmembrane glycoprotein which is restricted to B cell antigen. CD19 antigen is expressed on normal and neoplastic B cells and also in some bone marrow cells. CD19 expression by B progenitor cells is presumably at late pro-B or early pre-B stages around the time of Ig heavy chain rearrangement. Expression persists during all stages of B cell maturation and is lost on terminal differentiation to plasma cells. CD19 antigen is also found on the follicular dendritic cells and the early cells of myelomonocytic lineage but not on normal T cells, NK cells, monocytes, granulocytes, erythrocytes and platelets. In normal peripheral blood, 8-20% of lymphocytes express CD19 antigen. CD19 antigen plays a role in regulating B cell proliferation. |
| 克隆类型: | Rabbit Polyclonal Antibody, HRP-conjugated Antibody |
| 亚型: | Rabbit Ig |
| 免疫原: | KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD-19. |
| 适用物种: | H, M, R |
| 应用范围: | E, WB, IHC |
| 应用说明: | E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500 |
| 别名: | B-lymphocyte antigen CD19; Differentiation antigen CD19; B-lymphocyte surface antigen B4; Leu-12; CD19 antigen; CD19 |
| 形态: | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1% BSA and 0.02% gentamicin. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件: | Store at -20°C. Product is guaranteed 6 months from the date of shipment. |
| 参考文献: |
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文献和实验CD19 分子 CD19 常用单克隆抗体或代号: B4,Leu12 主要表达细胞: B,Pre,FDC [B] 分子质量(kDa)和结构: gp90(IgSF) 功 能: 与CD21、CD81组成复合物,调节B细胞活化 CD19 Response regulator that plays a dominant role in establishing signaling
在免疫反应方面,基于抗原的刺激在体内形成、并与抗原作特异性结合的蛋白质之总称。其化学实质是免疫球蛋白。抗体,按照抗原抗体反应的类型可分别称为沉淀素、凝集素、溶血素、溶菌素、抗毒素、中和抗体等,但这些并不等于有相应的不同抗体存在,一般多只表明抗体反应的多样性而已。抗体在血清中含量最多(体液抗体=humoral antibody);含有某特定抗体的血清称为抗血或免疫血清。
机体在抗原物质刺激下,由B细胞分化成的浆细胞所产生的、可与相应抗原发生特异性结合反应的免疫球蛋白。因为最初有人用电泳证明血清中抗体活性在γ球蛋白部分,故曾把抗体统称为两种(γ)球蛋白。后来证明,抗体并不都在γ区;而且位于γ区的球蛋白,也不一定都具有抗体活性。1964年,世界卫生组织举行专门会议,将具有抗体活性以及与抗体相关的球蛋白统称为免疫球蛋白(Ig)。如骨髓瘤蛋白,巨球蛋白血症、冷球蛋白血症等患者血清中存在的异常免疫球蛋白以及“正常人”天然存在的免疫
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