CD19分子
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CD19 分子
CD19
常用单克隆抗体或代号： B4,Leu12
主要表达细胞： B,Pre,FDC [B]
分子质量(kDa)和结构： gp90(IgSF)
功 能： 与CD21、CD81组成复合物,调节B细胞活化
CD19
Response regulator that plays a dominant role in establishing signaling thresholds for antigen receptors and other surface receptors on B cells; also regulates B cell development, activation and differentiation
CD19 antibody inhibits B cell activation from anti-immunoglobulin
Coreceptor with CD21
Earliest B cell antigen in fetal tissue
Positive staining (normal): Pre B, B cells; first B cell antigen after HLA-DR, follicular dendritic cells
Negative staining: plasma cells
