- ￥3000 - 3999
- Abbiotec
- 美国
- 252182
- 2025年07月12日
- E, WB, IHC
- Rabbit
- H
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- 详细信息
- 技术资料
- 免疫原：
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human osteoprotegerin.
- 亚型：
Rabbit Ig
- 形态：
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.5% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
- 保存条件：
Store at -20°C.
- 克隆性：
多克隆
- 标记物：
见下方详细说明
- 适应物种：
H
- 保质期：
1-2年
- 抗原来源：
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human osteoprotegerin.
- 目录编号：
252182
- 级别：
超纯
- 库存：
大量
- 供应商：
Abbiotec
- 宿主：
Rabbit
- 应用范围：
E, WB, IHC
- 浓度：
见详细说明信息
- 靶点：
Osteoprotegerin
- 抗体英文名：
Osteoprotegerin Antibody
- 抗体名：
Osteoprotegerin Antibody
- 规格：
0.1 mg
Osteoprotegerin Antibody产品详细介绍：
| 产品名称： | Osteoprotegerin Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 252182 |
| 规格： | 0.1 mg |
| 产品描述： | Osteoclastogenesis inhibitory factor (osteoprotegerin) acts as a decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Osteoprotegerin also acts as a decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis. Osteoprotegerin inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis depends on the local RANKL/osteoprotegerin ratio. Defects in osteoprotegerin are the cause of juvenile Paget disease (JPD). JPD is a rare autosomal recessive osteopathy that presents in infancy or early childhood. The disorder is characterized by rapidly remodeling woven bone, osteopenia, debilitating fractures, and deformities due to a markedly accelerated rate of bone remodeling throughout the skeleton. Unless it is treated with drugs that block osteoclast-mediated skeletal resorption, the disease can be fatal. |
| 克隆类型： | Rabbit Polyclonal Antibody |
| 亚型： | Rabbit Ig |
| 免疫原： | KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human osteoprotegerin. |
| 适用物种： | H |
| 应用范围： | E, WB, IHC |
| 应用说明： | E: 1:10,000-1:50,000; WB: 1:200-1:1,000; IHC: 1:50-1:200 |
| 别名： | Tumor necrosis factor receptor superfamily member 11B; Osteoprotegerin; Osteoclastogenesis inhibitory factor; TNFRSF11B; OCIF; OPG |
| 形态： | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.5% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography. |
| 保存条件： | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： |
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Osteoprotegerin Antibody_Osteoprotegerin抗体
￥3000 - 3999
