hN2 Human Neurons High Through

Use of Primary Human Cells in High-Throughput Screens

Traditionally, the objective of high-throughput screening (HTS) has been to identify compounds that interact with a defined target protein as the starting point for a chemistry lead optimisation programme. To enable

Introduction: Cell-Based Assays for High-Throughput Screening

Cell-based assays represent approximately half of all high-throughput screens (HTS) currently performed. Here we review the history and status of HTS, and summarize some of the challenges and benefits associated with the use

Design and Implementation of High Throughput Screening Assays

In most pharmaceutical and biotechnology companies, high throughput screening (HTS) is a central function in the drug-discovery process. This has resulted from the fact that there are increasing numbers of validated therapeutic targets