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文献和实验Gene and Enhancer Traps for Gene Discovery
Gene traps and enhancer traps provide a valuable tool for gene discovery. With this system, genes can be identified based solely on the expression pattern of an inserted reporter gene. The use of a reporter gene, such as β-glucuoronidase (GUS
Quantitative Trait Locus Analysis as a Gene Discovery Tool
in identifying genes that underlay complex traits. In this chapter, I will describe the basic steps required to conduct QTL analysis in crop plants. This process involves choices by the investigator on type of population to be studied, molecular marker
of technologies capable of identifying molecular biomarkers from the gene expression profiles of preserved surgical specimens. Molecular tests such as the Oncotype DX� breast cancer test are proving to be more effective tools for individualized patient
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