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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
单甲基化组蛋白 H3 K79 单克隆抗体(兔源)
- 抗体英文名:
MonoMethyl Histone H3 K79 Antibody, mAb, Rabbit
- 靶点:
单甲基化组蛋白 H3 K79
- 浓度:
0.5mg/mL(常规浓度,以官方说明书为准)
- 应用范围:
Western Blot、免疫细胞化学 / 免疫荧光 (ICC/IF)、免疫组化 (IHC)、免疫沉淀 (IP)
- 宿主:
兔(Rabbit)
- 适应物种:
人、小鼠、大鼠
- 保质期:
- 20℃可稳定保存 半 年
- 抗原来源:
人单甲基化组蛋白 H3 K79 合成肽
- 级别:
科研级
- 库存:
现货
- 供应商:
上海经科化学科技有限公司
- 标记物:
无(Unconjugated)
- 克隆性:
单克隆(Monoclonal)
- 保存条件:
-20℃,可稳定保存 半 年
- 形态:
液体(Liquid)
- 亚型:
Rabbit IgG
- 免疫原:
人单甲基化组蛋白 H3 K79 合成肽
- 规格:
50μl/100μl
| 规格: | 50μl | 产品价格: | ¥1200.0 |
|---|---|---|---|
| 规格: | 100μl | 产品价格: | ¥2200.0 |
| Specificity | This product is specific to MonoMethyl-Histone H3 (K79) |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human Histone H3.1 around the methylation site of K80 |
| Species Reactivity | Human; Mouse; Rat |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Buffer | Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Storage Instructions | Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed. |
| Purification | Affinity-chromatography |
| Isotype | Rabbit IgG |
| Clonality | Monoclonal |
| Target Background | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Synonyms | Histone H3.1, Histone H3, HIST1H3A; |
MonoMethyl-Histone H3 (K79) 抗体、单甲基化组蛋白 H3 K79 抗体、组蛋白 H3 抗体、单甲基化组蛋白 H3 抗体、兔源 MonoMethyl-Histone H3 (K79) 抗体、单克隆 MonoMethyl-Histone H3 (K79) 抗体、抗 MonoMethyl-Histone H3 (K79) 抗体、Histone H3 K79me1 抗体、表观遗传相关抗体、WB 抗体、IHC 抗体、IF 抗体
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文献和实验Competing Chromosomal Proteins from Drosophila Polytene Chromosomes Using Modified Histone Peptides
to chromatin, by its histone tail interaction or by other interactions, then you would not expect to see loss of binding upon peptide competition. A good positive control for the assay is to use H3K9 dimethylated peptide to compete HP1 from the pericentric
that was an interspecific hybrid (H) between Mus musculus domesticus (D, paternal genome) and Mus spretus (S, maternal genome). The native chromatin was then immunoprecipitated with rabbit polyclonal antisera to acetylation at lysine 9 of H3 (H3K9Ac) and to dimethylation
Nature:肿瘤和免疫细胞抢「蛋」?邹伟平谈肿瘤影响T细胞代谢和功能新机制
的直接调控。 图片来源:Nature 补充蛋氨酸可恢复 T 细胞抗肿瘤功能作者向小鼠肿瘤中注射了蛋氨酸,发现补充蛋氨酸可延缓肿瘤的生长,并可增强肿瘤浸润性 CD8+ T 细胞中 H3K79me2 以及 STAT5 的表达,提高 T 细胞存活率和细胞因子的表达。此外,蛋氨酸和 PD-L1 单抗还能起到协同的抗肿瘤作用。为结直肠癌病人补充蛋氨酸也能观察到类似的结果。图片来源:Nature 肿瘤细胞是如何「抢夺」蛋氨酸的?蛋氨酸通过溶质载体家族(SLC)转运到细胞中,该家族包括系统 L 型和 A 型转运
技术资料








