- ￥333 - 418
- TargetMol
- 美国
- T0923
- 2025年06月18日
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- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
Busulfan
- 库存：
10
- 供应商：
TargetMol
- CAS号：
55-98-1
- 规格：
1 mL/1 g/500 mg
| 规格： | 1 mL | 产品价格： | ￥418.0 |
|---|---|---|---|
| 规格： | 1 g | 产品价格： | ￥418.0 |
| 规格： | 500 mg | 产品价格： | ￥333.0 |
Product Introduction
Bioactivity
英文名:Busulfan
描述:Busulfan (Busulphan) is a synthetic derivative of dimethane-sulfonate with antineoplastic and cytotoxic properties. Although its mechanism of action is not fully understood, busulfan appears to act through the alkylation of DNA. Following systemic absorption of busulfan, carbonium ions are formed, resulting in DNA alkylation and DNA breaks and inhibition of DNA replication and RNA transcription.
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文献和实验Busulfan is a chemotherapy drug widely used as part of conditioning regimens for patients undergoing bone marrow transplantation (BMT). Challenges of busulfan treatment include a narrow therapeutic window and wide inter- and intra-patient
Dynamics of Claudins Expression in Colitis and Colitis-Associated Cancer in Rat
-7 were ubiquitously expressed in all study groups. As depicted in Fig. 1b, expressions of claudin-2, -12, and -15 significantly diminished after combined treatment with dextran sulfate sodium (DSS) and busulfan (BU) (lane 5), compared with either agent alone (lanes
。 环磷酰胺(cyclophosphamide)静脉注射,4mg/kg/日,每日或隔日一次,总量8～10g为一疗程。大剂量冲击疗法为10～20mg/kg/次,每周一次,8g为一疗程,以口服维持,2～4mg/kg/日,分次服用。 噻替派(thio-tepa)静脉注射、动脉注射或肌内注射,0.2mg/kg/次/日,连用5～7日,以后改为每周2～3次,总量约200～400mg。体腔注射,20～40mg/次,1～2次/周。 白消安(busulfan)口服,2～8mg/日,分3次空腹
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