重组人 NRG1-beta 1 蛋白 (EGF Domain, Fc标签)

重组人 NRG1-beta 1 蛋白 (EGF Domain, Fc标签)（产品说明）
蛋白名称：Human NRG1-beta 1 Protein (EGF Domain, Fc Tag)
蛋白构建：A DNA sequence encoding the EGF-like domain (Thr 176-Lys 246) of human NRG1 isoform beta1 (Q02297-6) was fused with the Fc region of human IgG1 at the N-terminus.
表达宿主：HEK293 Cells
蛋白纯度：> 86 % as determined by SDS-PAGE
蛋白活性：1. Measured by its binding ability in a functional ELISA. 2. Immobilized Rhesus ErbB3 at 2 μg/mL (100 μl/well) can bind human NRG1 (isoform Beta1), The EC50 of human NRG1 (isoform Beta1) is 0.58 μg/mL. 3. Immobilized human ErbB3 at 2 μg/mL (100 μl/well) can bind human NRG1 (isoform Beta1), The EC50 of human NRG1 (isoform Beta1) is 0.43 μg/mL.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Glu
蛋白分子量：The recombinant human NRG1（aa176-246）/Fc chimera is a disulfide-linked homodimeric protein. The reduced monomer consists of 331 amino acids and has a calculated molecular mass of 36.7 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh NRG1/Fc monomer is approximately 38 kDa.
蛋白NP号：Q02297-6
蛋白氨基酸序列：Thr176-Lys246
蛋白标签：N-human IgG1-Fc
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.