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- 规格:
20 µg/50 µg
| 规格: | 20 µg | 产品价格: | ¥2310 |
|---|---|---|---|
| 规格: | 50 µg | 产品价格: | ¥3870 |
蛋白名称:Factor VII蛋白, Factor VII protein
蛋白构建:A DNA sequence encoding the mouse FⅦ (NP_034302.2) (Met 1-Leu 446) was fused with the a polyhistidine tag at the C-terminus.
表达宿主:CHO Stable Cells
蛋白纯度:> 90 % as determined by SDS-PAGE
蛋白活性:Measured by its binding ability in a functional ELISA. Immobilized mouse F7-his at 10 μg/ml (100 μl/well) can bind biotinylated mouse F3-his (Cat:50413-M08H). The EC50 of biotinylated mouse F3-his (Cat:50413-M08H) is 0.1-0.3 μg/ml.
蛋白内毒素:< 1.0 EU per μg of the protein as determined by the LAL method
预测N端:Val 25 & Ala 42
蛋白分子量:The mature form of mouse FⅦ consists of 416 amino acids after removal of the signal peptide and the propeptid, and has a predicted molecular mass of 47 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm FⅦ is approximately 56-63 kDa due to glycosylation.
蛋白NP号:NP_034302.2
蛋白氨基酸序列:Met1-Leu446
蛋白标签:C-His
蛋白保存条件:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验Identification of Mutations in the Human Factor VII Gene
It has been recognized from the early 1800s that activation of coagulation can be initiated by the exposure of subendothelial layers (tissue factor), but it was the 1940s before factor VII (FVII) was included in this event
Sequencing exon by exon to identify mutations is both laborious and time consuming. Screening techniques have been sought to identify mutations without the need for this. Rapid detection of single base changes have focused on identification
Tissue Factor/VIIa in Thrombosis and Cancer
Tissue factor (TF) is a transmembrane glycoprotein that functions as a receptor and cofactor for activated factor VII (factor VIIa) to initiate blood coagulation. Although TF has been characterized best for its role in blood coagulation
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