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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 保存条件:
-20℃ to -80℃
- 保质期:
12个月
- 英文名:
Recombinant Human β-NGF / Beta-NGF Protein
- 库存:
99
- 供应商:
北京义翘神州科技股份有限公司
- 规格:
1.00 mg/20.00 µg/100.00 µg/500.00 µg
| 规格: | 1.00 mg | 产品价格: | ¥8980.0 |
|---|---|---|---|
| 规格: | 20.00 µg | 产品价格: | ¥580.0 |
| 规格: | 100.00 µg | 产品价格: | ¥1580.0 |
| 规格: | 500.00 µg | 产品价格: | ¥4480.0 |
蛋白名称:Human β-NGF / Beta-NGF Protein
蛋白构建:A DNA sequence encoding the mature form of human β-NGF (NP_002497.2) (Ser 122-Arg 239) was expressed.
表达宿主:CHO Stable Cells
蛋白纯度:> 95 % as determined by SDS-PAGE
蛋白活性:Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is typically 0.2-2 ng/ml.
蛋白内毒素:< 1.0 EU per μg of the protein as determined by the LAL method
预测N端:Ser 122
蛋白分子量:The mature recombinant human β-NGF consists of 118 amino acids and has a predicted molecular mass of 13.2 kDa. β-NGF exists as a non-disulfide linked homodimer in solution.
蛋白NP号:NP_002497.2
蛋白氨基酸序列:Ser122-Arg239
蛋白标签:Native
蛋白保存条件:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验2, Zheng, Z; et al. Histone deacetylase 6 inhibition restores autophagic flux to promote functional recovery after spinal cord injury. Experimental neurology, PMID: 31794745
3, Zhou, K; et al. TFE
3, a potential therapeutic target for Spinal Cord Injury via augmenting autophagy flux and alleviating ER stress. Theranostics, PMID: 32802192
4, Liao, S; et al. A bionic multichannel nanofiber conduit carrying Tubastatin A for repairing injured spinal cord. Materials today. Bio, PMID: 36310542
5, Lu, E; et al. Stub1 ameliorates ER stress-induced neural cell apoptosis and promotes locomotor recovery through restoring autophagy flux after spinal cord injury. Experimental neurology, PMID: 37495008
6, Cheng, C; et al. Nerve growth factor promote osteogenic differentiation of dental pulp stem cells through MEK/ERK signalling pathways. Journal of cellular and molecular medicine, PMID: 38333908
7, Fang, Z; et al. Topical TYK2 inhibitor ameliorates psoriasis-like dermatitis via the AKT-SP1-NGFR-AP1 pathway in keratinocytes. Clinical and translational medicine, PMID: 40038877
8, Fang, Z; et al. Topical TYK2 inhibitor ameliorates psoriasis-like dermatitis via the AKT-SP1-NGFR-AP1 pathway in keratinocytes. Clinical and translational medicine, PMID: 40038877
9, Su, H; et al. A self-assembling peptide-based hydrogel containing NF-κB inhibitors and NGF for peripheral nerve injury repair. Biofabrication, PMID: 40145273
10, Yang, J; et al. Nuclear MicroRNA-124-3p Promotes Neurite Outgrowth After Spinal Cord Injury by Enhancing Cttn Transcription. Molecular neurobiology, PMID: 40044957
11, Zou, Z; et al. miR-218a-5p derived from neural stem cell-exosomes inhibits ferroptosis in spinal cord injury through the Bmil/Mettl3/Alox12 axis. International journal of biological macromolecules, PMID: 41067360
attenuator 有一个问题一直没有查出相关资料或信息。 就是:β globin 蛋白在血液组织之外的细胞有没有表达,能不能RT检测出transcripts或western检测出protein。 为了这个去重复实验,条件不允许,但前人肯定有做过的,教科书里没有介绍,只介绍了时间特异性(胚胎到成体),没有介绍组织特异性——除了造血组织(或成红祖细胞)之外,在其他组织里,β globin是不是就沉默了,它那一簇基因是不是从它LCR
Mutation Analysis in -Sarcoglycan (LGMD2F)
encoding dystrophin-associated glycoproteins (1 –3 , and references therein). Mutations in -sarcoglycan (SG) (4 ,5 ) β -SG (6 ,7 ) γ -SG (8 ),δ -SG (9 ) cause LGMD2D, LGMD2E, LGMD2C, and LGMD2F, respectively. In these forms, when any SG is missing
蛋白质或多肽链的二级结构之一。原来是与α结构相对而命名为β结构,前者指多肽链折叠而后者指具有伸长的多肽链的结构。其后由 L. Pauling和 R. B. Corey指出如下的模型,即β结构因在链间形成氢键而成为薄板状,而且有摺,因而称为打摺薄板状结构。此时相邻的二条多肽链,有时互相平行,有时是反平行的,分别称之为平行打摺结构和反平行打摺结构。然而现在多将此称为平行β结构和反平行β结构。这样的β结构见于纤维状蛋白质或热变性的蛋白质。但在球状蛋白质中,有以一条多肽链呈发夹状
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