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100 µL
抗体种属:Rhesus
抗体靶点:ERBB2
抗体应用:ELISA
抗原货号:90020-K08H
抗原描述:Recombinant Rhesus HER2 / ErbB2 protein (Catalog#90020-K08H)
抗体宿主:Rabbit
抗体Ig类型:Rabbit IgG
抗体纯化方法:Protein A
抗体制备:Produced in rabbits immunized with purified, recombinant Rhesus HER2 / ErbB2 (rh ERBB2; Catalog#90020-K08H; XP_001090430.1; Met1-Thr652). Total IgG was purified by Protein A affinity chromatography.
抗体特异性:Rhesus HER2 / ErbB2
抗体保存:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
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文献和实验Assay for Isolation of Inhibitors of Her2-Kinase Expression
Her2 (ErbB2) protein is overexpressed in breast and other solid tumors, and its expression is associated with progressive disease. Current therapies directed toward Her2 either block dimerization of the receptor or inhibit tyrosine kinase
Automated Analysis of FISH-Stained HER2/neu Samples with Metafer
The HER2/neu gene (also known as ERBB2) is located on chromosome 17 (q11.2–q12) and encodes a glycoprotein known to be a member of the epidermal growth factor receptor family. Clinically, the determination of its amplification status
Her2为啥是ErbB信号通路的关键呢?因为没有她,就没法穿搭……
ErbB信号通路,是个做妇科肿瘤常见的信号通路,特别是乳腺癌研究中,对HER2的研究都很常见。为啥HER2(也就是ErbB2)的研究会这么多,这和ErbB信号通路本身是分不开的。我们先来看看ErbB信号通路是什么鬼?嗯,这个复杂程度,就有点令人发指了,不光是进入细胞后的内容丰富,膜受体也是特别复杂。夏老师给你们稍微简化一下,差不多就是这样:还是有点复杂,不是么?实际上,造成ErbB信号通路这么复杂的原因,主要就是ErbB信号通路的膜受体,一共有这么四种:ErbB1(也就是EGFR),ErbB2
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