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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20℃
- 保质期:
12个月
- 英文名:
Recombinant Interleukin 17 (IL17)
- 库存:
1000
- 供应商:
上海信裕
| Organism species | Mus musculus (Mouse) |
| Product No. | xy063Mu02 |
| Source | Prokaryotic expression |
| Host | E.coli |
| Purity | >95% |
| UOM | 50ug |
| Predicted Molecular Mass | n/a |
| Concentration | n/a |
| Applications | SDS-PAGE; WB; ELISA; IP. |
| Endotoxin Level | <1.0EU per 1µg (determined by the LAL method) |
| Formulation | Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl. |
Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37oC for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and 70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at double intensity to make location and size approximation of proteins of interest quick and easy.
白介素17(IL17)重组蛋白Ready-to-use: No need to heat, dilute or add reducing agents before use.
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文献和实验Immunity:「填补教科书」董晨院士团队解析 IL-17D 重要功能,并首次发现其受体
慢性炎症与自身免疫性疾病、过敏性疾病和肿瘤的发展密切相关,炎性因子白介素 - 17(IL-17)家族在促进宿主防御和自身免疫性疾病中起着重要作用。IL-17 家族由六个成员组成(包括 IL-17A、B、C、D、E、F),IL-17D 是 IL-17 家族中了解最少的成员,其受体也尚不明确。 图片来源:Frontiers in Immunology(1)2021 年 4 月 13 日,清华大学医学院董晨院士团队在 Immunity 上在线发表了题为 Interleukin-17
白细胞介素 IL-17 IL-17主要产生细胞:活化CD4+T细胞 IL-17氨基酸数目:前体为155 (二聚体) IL-17分子质量(kDa):15-20/32 IL-17受体:IL-17RA;IL17RC IL-17主要生物学活性:激活NF-κB;诱导成纤维细胞IL-6、IL-8、GM-CSF和PGE2的分泌和ICAM1表达;协同刺激活化的T细胞增殖
【求助】我要RORγt的基因序列号,可是在NCBI上检索出来的只有RORC,请问是一回事吗?
_001001523.1 再点进去,发现就是RORC,同时还有很多其他名称 TOR; Thor; Nr1f3; RORgamma; Rorc,都是同一样东西。 见以下参考文献 1. In cooperation with RORgammat and RORalpha, IkappaBzeta enhances Il17a expression by binding directly to the regulatory region of the Il17a gene
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