MMP-9 Antibody
Cat#:PL0304134
Isotype:Rabbit Polyclonal IgG
Immunogen:Peptide derived from human MMP9 C-terminus.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
All cells within tissues are surrounded by an extracellular matrix (ECM) giving the tissues shape and structure. The ECM is constantly being remodeled and constant communication is maintained between cells through this matrix. Secreted proteins, termed matrix metalloproteinases (MMPs), are involved in the modulation of cell matrix interactions. MMPs are Zn(2+) binding endopeptidases that degrade various components of the ECM. MMPs are enzymes implicated in normal and pathologic tissue remodeling processes, wound healing, angiogenesis, and tumor invasion. These enzymes are very potent when active, and are associated with extracellular space inhibitors called TIMPs (tissue inhibitors of matrix metalloproteinases).
Alternate Names:
Matrix metalloproteinase-9 precursor; MMP-9; MMP9; MMP 9; 92 kDa type IV. Collagenase; 92 kDa gelatinase; Gelatinase B; GELB; MMP9_HUMAN; Matrix metalloproteinase-9; 92 kDa type IV collagenase; Gelatinase B; 67 Da matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9.
Specificity Reaction:Hu, Mo, Rat, Dog, Pig, Cow, Hor, Guinea Pig
Application Notes:E: 1:500-1000 IHC: 1:100-500 IF: 1:100-500
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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