- ￥2400
- PL Laboratories
- 加拿大
- PL0302304
- 2025年07月15日
- WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500
- Rabbit
- Hu, Mo, Rat, Chi, Dog, Hor
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- 详细信息
- 技术资料
- 免疫原：
PhosphoPeptide derived from human Crk p38 around the phosphorylation site of Tyr221 [GP(p-Y)AQ].
- 亚型：
Rabbit Polyclonal IgG
- 形态：
液态
- 保存条件：
保存于-20℃
- 克隆性：
多克隆
- 标记物：
无标记（PLlabs可供应生物素、酶、荧光素标记的抗体）
- 适应物种：
Hu, Mo, Rat, Chi, Dog, Hor
- 保质期：
按说明书条件可保存1-2年
- 抗原来源：
见详细说明资料
- 目录编号：
PL0302304
- 级别：
超纯
- 库存：
大量
- 供应商：
华拓生物
- 宿主：
Rabbit
- 应用范围：
WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500
- 浓度：
1mg/ml
- 靶点：
phospho-Crk p38 (Tyr221)
- 抗体英文名：
phospho-Crk p38 (Tyr221) Antibody
- 抗体名：
磷酸化Crk p38抗体
- 规格：
0.1ml
phospho-Crk p38 (Tyr221) Antibody
Cat#：PL0302304
Isotype:Rabbit Polyclonal IgG
Immunogen：PhosphoPeptide derived from human Crk p38 around the phosphorylation site of Tyr221 [GP(p-Y)AQ].
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
Crk p38 (CrkII) is an isoform of the protein Crk. CrkI and CrkII are produced from the same crk gene by alternative splicing. The two isoforms differ in their biological activities with CrkII having less transforming activity than CrkI. Crk p38 is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. It has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Crk is believed to be a regulator of invasive responses because increased levels of the protein have been observed in multiple human cancers.
Alternate Names：
Crk p38 (phospho Y221); p-Crk p38 (phospho Y221); p-CRK(phospho-Tyr221); p-CRK(phospho-Y221); Crk p38; CRK CRK isoform 2; CRK isoform II; CRKII; p38; Proto oncogene C crk; v crk avian sarcoma virus CT10 oncogene homolog ; v crk sarcoma virus CT10 oncogene homolog; v crk sarcoma virus CT10 oncogene homolog (avian); Adapter molecule crk; Avian sarcoma virus CT10 (v crk) oncogene homolog; CRK_HUMAN
Specificity Reaction：Hu, Mo, Rat, Chi, Dog, Hor
Application Notes:WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500
Storage ：
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
PLlabs公司可供应相应抗体的生物素、辣根过氧化物酶、荧光素（FITC、PE、 CY3、 CY5、 CY7、 PE- CY3/5/7)标记抗体，欢迎大家咨询订购。
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磷酸化Crk p38抗体
￥2400
