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- 详细信息
- 询价记录
- 技术资料
- 免疫原:
peptide corresponding to a sequence in the middle region of rat NOX1.
- 亚型:
Rabbit Polyclonal IgG
- 形态:
液态
- 保存条件:
保存于-20℃
- 克隆性:
多克隆
- 标记物:
无标记(PLlabs可供应生物素、酶、荧光素标记的抗体)
- 适应物种:
Mo, Rat
- 保质期:
按说明书条件可保存1-2年
- 抗原来源:
见详细说明资料
- 目录编号:
PL0402308
- 级别:
超纯
- 库存:
大量
- 供应商:
华拓生物
- 宿主:
Rabbit
- 应用范围:
WB: 1:100-500 IHC: 1:500-1000
- 浓度:
1mg/ml
- 靶点:
NOX1
- 抗体英文名:
NOX1 Antibody
- 抗体名:
NOX1抗体
- 规格:
0.1ml
NOX1 Antibody
Cat#:PL0402308
Isotype:Rabbit Polyclonal IgG
Immunogen:peptide corresponding to a sequence in the middle region of rat NOX1.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
NOX1(NADPH OXIDASE 1),also known as NOH1, MOX1 or GP91-2, is an enzyme that in humans is encoded by the NOX1 gene. It is also a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox.The NOX1 gene is mapped to Xq22.1. NOX1 was expressed in colon, prostate, uterus, and vascular smooth muscle, but not in peripheral blood leukocytes. The deduced 564-amino acid NOX1 protein, which is 58% identical to CYBB, contains 6 membrane-spanning regions, conserved flavin and pyridine nucleotide-binding sites, and histidines possibly involved in heme ligation. Overexpression of MOX1 in NIH 3T3 cells increased superoxide generation and cell growth. Cells expressing MOX1 had a transformed appearance, showed anchorage-independent growth, and produced tumors in athymic mice. Disruption of either Nox1 or Nox2 significantly delayed progression of motor neuron disease in these mice. However, 50% survival rates were enhanced significantly more by Nox2 deletion than Nox1 deletion.
Alternate Names:
GP91 2 antibody;Mitogenic oxidase(pyridine nucleotide dependent superoxide generating) antibody;Mitogenic oxidase 1 antibody; MOX1 antibody;NADH/NADPH mitogenic oxidase subunit P65 MOX antibody; NADPH oxidase 1 antibody;NADPH oxidase 1 variant NOH 1L antibody;NADPH oxidase homolog 1 antibody;NOH 1 antibody; NOH1 antibody;Nox1 antibody;NOX1_HUMAN antibody.
Specificity Reaction:Mo, Rat
Application Notes:WB: 1:100-500 IHC: 1:500-1000
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
PLlabs公司可供应相应抗体的生物素、辣根过氧化物酶、荧光素(FITC、PE、 CY3、 CY5、 CY7、 PE- CY3/5/7)标记抗体,欢迎大家咨询订购。
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NOX1抗体
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