Recombinant Human Interleukin-7, Saccharomyces产品图

Recombinant Human Interleukin-

7, Saccharomyces
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  • ¥1680 - 3988
  • 美国ATCC
  • 美国/中国
  • YB-0898
  • 2026年05月21日
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    上海钰博生物科技有限公司
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    • 文献和实验
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    • 库存：

      大量

    • 供应商：

      钰博生物

    • 细胞类型：

      复苏

    • 组织来源：

      见说明书

    • 物种来源：

      人、大鼠、小鼠、、、、

    • 免疫类型：

      请咨询销售人员

    • 细胞形态：

      上皮样；多角形

    • 是否是肿瘤细胞：

      见说明书

    • 器官来源：

      见说明书

    • 运输方式：

      干冰运输or活细胞运输

    • 年限：

      见说明书

    • 生长状态：

      贴壁生长

    Recombinant Human Interleukin-7, Saccharomyces
    Synonyms Lymphopoietin 1 (LP-1), pre-B cell factor, IL-7.
    Introduction IL-7 is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival.
    Recombinant Human Interleukin-7, SaccharomycesDescription Interleukin-7 Human Recombinant produced in yeast is a single, glycosylated polypeptide chain containing 152 amino acids and having a molecular mass of 17.4 kDa. The IL-7 is purified by proprietary chromatographic techniques.
    Source Saccharomyces cerevisiae.
    Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
    Formulation Lyophilized from a concentrated (1mg/ml) solution in water containing 20mM phosphate buffer.
    Recombinant Human Interleukin-7, SaccharomycesSolubility It is recommended to reconstitute the lyophilized Interleukin -7 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
    Stability Lyophilized Interleukin-7 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL7 should be stored at 4°C between 2-7 days and for future use below -18°C.
    For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
    Please prevent freeze-thaw cycles.
    Purity Greater than 98.0% as determined by SDS-PAGE.
    Amino acid sequence The sequence of the first five N-terminal amino acids was determined and was found to be Asp-Cys-Asp-Ile-Glu.
    Biological Activity The ED50 as determined by the dose-dependent stimulation of thymidine uptake by murine pre-B cell line 2E8 is < 0.5 ng/mL, corresponding to a specific activity of 2MU/mg.
    Recombinant Human Interleukin-7, SaccharomycesProtein content Protein quantitation was carried out by two independent methods
    1. UV spectroscopy at 280 nm using the absorbency value of 0.418 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics).
    2. Analysis by RP-HPLC, using a standard solution of IL-7 as a Reference Standard.
    Usage CHI's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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