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α-Synuclein Antibody

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  • 询价
  • Cell Signaling Technology已认证
  • USA
  • 2025年08月13日
  • W, IP
  • Rabbit
  • H,M,R,Mk
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 抗体英文名

      α-Synuclein Antibody

    • 抗原

      synthetic peptide corresponding to the carboxy-terminal sequence of human α-synuclein

    • 应用范围

      W, IP

    • 宿主

      Rabbit

    • 库存

      大量

    • 适应物种

      H,M,R,Mk

    • 保质期

      详见说明书

    • 级别

      详见MSDS文件

    • 供应商

      CST

    • 是否单克隆

      2

    • 保存条件

      -20°c

    • 规格

      100 ul (10 western blots)/carrier free & custom formulation / quantity

    规格:产品价格:¥请询价
    规格:100 ul (10 western blots)产品价格:¥请询价
    规格:carrier free & custom formulation / quantity产品价格:¥请询价

    pathway more info application references datasheet PDF MSDS PDF protocols

    Applications Key:  W=Western Blotting  IP=Immunoprecipitation
    Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Monkey
    Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.

    Applications Reactivity Sensitivity MW (kDa) Source
    W IP H M R Mk Endogenous 18 Rabbit
    Protocols
    Specificity / Sensitivity

    α-Synuclein Antibody detects the alpha isoform of synuclein. The antibody may cross-react with β-synuclein.

    Source / Purification

    Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the carboxy-terminal sequence of human α-synuclein. Antibodies are purified by protein A and peptide affinity chromatography.

    Western Blotting

    Western Blotting

    Western blot analysis of extracts from 293, HeLa, rat brain and mouse brain cell extracts, using α-Synuclein Antibody.

    IP

    IP

    Immunoprecipitation of α-synuclein from HeLa cell extracts, using α-Synuclein Antibody. Lane 1 is lysate control, lane 2 is antibody alone and lane 3 is both antibody and lysate.

    Background

    α-Synuclein is a protein of 140-amino acids expressed abundantly in the brain. α-Synuclein is also the main component of pathogenic Lewy bodies and Lewy neurites. Research studies have shown that mutations of the α-synuclein gene are linked to Parkinson's disease (1).

    1. Goldberg, M.S. and Lansbury Jr., P.T. (2000) Nat. Cell Biol. 2, 115-119.
    Application References

    Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know !

    Companion Products

    For Research Use Only. Not For Use In Diagnostic Procedures.

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    图标文献和实验
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