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- Cell Signaling Technology
- USA
- 6993S
- 2026年01月22日
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文献和实验Integrin-Targeted Nanoparticles for siRNA Delivery
Integrins are heterodimeric membrane glycoproteins composed of noncovalently associated α and β subunits. Integrins support cell attachment and migration on the surrounding extracellular matrix as well as mediate cell–cell interaction
Inducing RNAi with siRNA Cocktails Generated by RNase III
products (21 bp range) can effectively mediate RNAi in both mammalian cells (10) and mouse embryos (11). We demonstrate here that the siRNA cocktails produced by complete digestion by RNase III (~12 to 15 bp) are capable of silencing specific genes
eliminate the guesswork--and the tedious labwork--associated with siRNA design and testing. Applied Biosystems' gene-specific, ready-to-run TaqMan® Gene Expression Assays provide you with a fast, simple way to measure the efficacy of mRNA knockdown
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