Liothyronine三碘甲状腺原氨酸,6893-02-3

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Liothyronine

CAS No. : 6893-02-3

MCE 国际站：Liothyronine

产品活性：Liothyronine 是一种有效的甲状腺激素。Liothyronine 是有效的 TRα 和 TRβ 激动剂，对 hTRα 和 hTRβ 的 K_i 值均为 2.33 nM。

研究领域：Vitamin D Related/Nuclear Receptor  |  Metabolic Enzyme/Protease

作用靶点：Thyroid Hormone Receptor  |  Endogenous Metabolite

结构分类：酚类  |  单酚类  |  酮、醛、酸  |  结构分类

In Vitro: hepatocarcinomaLiothyronine (T3, 100 nM) stimulates the proliferation of hepatocarcinema cells in which TRβ1 is overexpressed. Liothyronine binds to the human β1 thyroid hormone receptor (hTRβ1), and changes its conformation. Liothyronine promotes growth, induces differentiation and regualtes metabolic effects.

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