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Stemolecule Sodium Butyrate

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  • 询价
  • ATCC
  • 美国/中国
  • xy-04-0005
  • 2025年07月15日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      4℃保存

    • 保质期

      6个月

    • 英文名

      Stemolecule Sodium Butyrate

    • 库存

      1

    • 供应商

      上海信裕

    • Stemolecule Sodium Butyrate保存于运输说明:
    • 4°C protected from light. Following reconstitution, store aliquots at -20°C
    • 详细信息:
    • Stemolecule™ Sodium Butyrate

      Sodium butyrate is the sodium salt of the short-chain fatty acid butyric acid1. Butyrate is a metabolite of intestinal bacteria and a major energy source for gut epithelial cells, and is known to play a key role in the homeostasis of the gastrointestinal tract2. The effects of sodium butyrate on cell volume regulation and chloride transport in the rat distal colon were first described by M. Diener et al. in 19973. Sodium butyrate is a known inhibitor of histone deacetylases4,5. The enhancement and suppression of various cytokines in stimulated human monocytes using sodium butyrate was first reported in 20002. In cultured mouse and human cells, sodium butyrate has been shown to inhibit both the mRNA and protein level of cyclin D16. View Poster

      Stemolecule Sodium Butyrate产品参数

      Chemical Formula C4H7NaO2
      Structure
      Molecular Weight 111.1
      CAS Number 156-54-7
      PubChem Substance ID 24891873
      Purity >98% by titration
      Formulation Stemolecule Sodium Butyrate White solid
      Solubility Soluble in DMSO (100 mM). For a 10 mM concentrated stock solution, reconstitute the compound by adding 4500 µl of DMSO to 5 mg of compound. Note: for most cells, the maximum tolerance to DMSO is <0.5%.
      Storage 4°C protected from light. Following reconstitution, store aliquots at -20°C
      Stability Stock solutions stable at -20°C for 6 months
      Quality Control The purity of sodium butyrate was determined by HPLC analysis. The accurate mass and structure of sodium butyrate was determined by mass spectrometry and NMR, respectively. Cellular toxicity of sodium butyrate was tested by using HeLa and HEK293 cells.
      References
      1. Kolthoff, I. M. et al., Quantitative Chemical Analysis, 4th ed., MacMillan Pub. (New York, NY: 1969).
      2. Saemann, M. D. et al., FASEB J., 14(15):2380-2382 (2000).
      3. Diener, M., and Scharrer, E., Biochem. Physiol. A Physiol., 118(2):375-379 (1997).
      4. Kruh, J., Mol. Cell. Biochem. ,42(2):65-82 (1982).
      5. Ware C.B., Wang L., Mecham B.H., Shen L., Nelson A.M., Bar M., Lamba D.A., Dauphin D.S., Buckingham B., Askari B., Lim R., Tewari M., Gartler S.M., Issa J.P., Pavlidis P., Duan Z., Blau C.A. (2009) Histone deacetylase inhibition elicits an evolutionarily conserved self-renewal program in embryonic stem cells. Cell Stem Cell 4(4):359-69.
      6. Lallemand, F. et al., Biochem. Biophys. Res. Commun., 229(1):163-169 (1996).
    • Stemolecule Sodium Butyrate
    • xy-1191xy IL-2 (Interleukin-2)Mouse、Ret白介素2抗原(大、小鼠)
      xy-0605xy IL-2 (Interleukin-2)HumanIL-2抗原(人)
      xy-1193xy IL-23(Interleukin-23)白介素-23抗原
      xy-0581xy IL-4(Interleukin-4)白介素4抗原
      xy-1740xy IL-4(Interleukin-4)human peptide白介素4抗原
      xy-1318xy IL-5 peptide白细胞介素5抗原
      xy-0781xy IL-6 (Interleukin-6) Human白介素6
      xy-1811xy IL-7(Interleukin-7)白介素7抗原
      xy-1805xy IL-6R Alpha (IL6R-alpha)白细胞介素6受体α抗原
      xy-1459xy gp130/IL-6R白介素-6受体抗原
      xy-1540xy IL-7Ra/CD127 peptide白细胞介素-7受体a抗原
      xy-1291xy ING1/p33(inhibitor of growth gene 1)生长抑制因子基因1抗原
      xy-1032xy Inhibin Alpha抑制素α抗原
      xy-1774xy Inhibin beta A peptide抑制素beta A抗原
      xy-1825xy Inhibin beta B抑制素βB抗原
      xy-2093xy Integrin Alpha3整合素α3抗原
      xy-2094xy Integrin Beta5整合素β5抗原
      xy-2095xy Integrin alpha 1整合素α1抗原
      xy-1051xy Integrin Alpha4 Beta7/LPAM-1 (Lymphocyte Peyer’s patch Adhesion Molecule 1/Integrin alpha4,beta7)整合素α4β7抗原
      xy-1274xy Integrin AlphaE2/CD103整合素αE2抗原
      xy-1568xy ENPP3/CD203c(ectonucleotide pyrophosphatase/phosphodiesterase 3)ENPP3抗原
      xy-1109xy IQGAP1支架蛋白抗原
      xy-1404xy IRF-1(Interferon regulatory factor-1)干扰素调节因子抗原
      xy-1427xy IRAK 2白介素-1受体相关激酶2
      xy-2216xy IL-1RA (Interleukin-1 receptor antagonist)peptide白介素-1受体拮抗剂抗原
      xy-1816xy Integrin a7(integrin alpha 7)整合素α7抗原
      xy-0486xy integrin Beta1(ITG- Beta1/CD29)粘附分子整合素β1抗原
      xy-0567xy Integrin Alpha5(ITG- AlphaV/CD49e)粘附分子整合素α5抗原
      xy-2250xy Integrin alpha V/CD51 peptide整合素αV抗原
      xy-1439xy JAK1(Tyrosine-protein kinase JAK1; Janus kinase 1)蛋白质酪氨酸激酶JAK-1抗原
      xy-0908xy JAK2(Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2)蛋白质酪氨酸激酶JAK-2抗原
      xy-2485xy phospho JAK2(phospho-Tyr1007+Tyr1008)磷酸化蛋白酪氨酸激酶JAK-2抗原
      xy-0501xy JNK1/3 (c-Jun amino-terminal kinase 1/3)c-Jun氨基末端激酶1/3多肽抗原
      xy-1640xy phospho-JNK1/2/3(pThr183/pTyr185) peptide磷酸化氨基末端激酶1/2/3(pJNK1/2/3)抗原
      xy-2130xy Ki-67(Antigen identified by monoclonal antibody Ki 67)Ki-67 Antigen

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