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Biotinylated Human PCSK9(CA84)

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  • ¥2300 - 6210
  • SinoBio
  • 国产
  • CA84
  • 2025年12月26日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      蛋白表达区间:Gln31-Gln692(Val474Ile,Gly670Glu)

    • 保质期

      See instructions

    • 英文名

      标签:C-Avi

    • 库存

      表达系统:Human Cells

    • 供应商

      上海经科化学科技有限公司

    • 规格

      20ug/100ug

    规格:20ug产品价格:¥2300.0
    规格:100ug产品价格:¥6210.0
    产品描述
    Biotinylated Recombinant Human Proprotein Convertase Subtilisin/Kexin Type 9 is produced by our Mammalian expression system and the target gene encoding Gln31-Gln692(Val474Ile,Gly670Glu) is expressed with a Avi tag at the C-terminus.
    蛋白编号
    Q8NBP7
    产品别称
    Proprotein Convertase Subtilisin/Kexin Type 9; Neural Apoptosis-Regulated Convertase 1; NARC-1; Proprotein Convertase 9; PC9; Subtilisin/Kexin-Like Protease PC9; PCSK9; NARC1
    偶联
    Biotinylated
    分子量
    14&59 KDa
    表观分子量
    19&65 KDa, reducing conditions
    剂型描述
    Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, 20% Glycerol, pH 7.4.
    内毒素
    < 1 EU/µg as determined by LAL test.
    纯度-SDS-PAGE
    Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
    运输条件
    • The product is shipped on dry ice/polar packs.
    • Upon receipt, store it immediately at the temperature listed below.
    保存条件
    • Store at ≤-70°C, stable for 6 months after receipt.
    • Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
    • Please minimize freeze-thaw cycles.
    产品背景
    Human Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. Inhibition of PCSK9 function by preventing PCSK9/LDLR interaction is currently being explored as a means of lowering cholesterol levels. PCSK9 also binds to apolipoprotein receptor 2 (ApoER2), and play a role in the neural development.

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    图标文献和实验
    该产品被引用文献

    Human Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. Inhibition of PCSK9 function by preventing PCSK9/LDLR interaction is currently being explored as a means of lowering cholesterol levels. PCSK9 also binds to apolipoprotein receptor 2 (ApoER2), and play a role in the neural development.

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    文献支持
    Biotinylated Human PCSK9(CA84)
    ¥2300 - 6210