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Human IL-6

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  • ¥936 - 14080
  • SinoBio
  • 国产
  • C009
  • 2025年12月21日
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    • 保存条件

      蛋白表达区间:Val30-Met212

    • 保质期

      See instructions

    • 英文名

      标签:Tag free

    • 库存

      表达系统:E.coli

    • 供应商

      上海经科化学科技有限公司

    • 规格

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥936.0
    规格:50ug产品价格:¥2800.0
    规格:500ug产品价格:¥9840.0
    规格:1mg产品价格:¥14080.0
    产品描述
    Recombinant Human Interleukin-6 is produced by our E.coli expression system and the target gene encoding Val30-Met212 is expressed.
    蛋白编号
    P05231
    产品别称
    Interleukin-6; IL-6; B-Cell Stimulatory Factor 2; BSF-2; CTL Differentiation Factor; CDF; Hybridoma Growth Factor; Interferon Beta-2; IFN-Beta-2; IL6; IFNB2
    偶联
    Unconjugated
    分子量
    20.9 KDa
    表观分子量
    20 KDa, reducing conditions
    剂型描述
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    内毒素
    < 0.01 EU/µg as determined by LAL test.
    纯度-SDS-PAGE
    Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
    生物活性-Cell Based Assay
    Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is 20-100 pg/ml. (QC verified)
    复溶
    • Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
    • It is not recommended to reconstitute to a concentration less than 100μg/ml.
    • Dissolve the lyophilized protein in distilled water.
    • Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
    运输条件
    • The product is shipped at ambient temperature.
    • Upon receipt, store it immediately at the temperature listed below.
    保存条件
    • Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
    • Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
    • Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    产品背景
    Cytokines of the IL6/GCSF/MGF family are glycoproteins of about 170 to 180 amino acid residues that contain four conserved cysteine residues involved in two disulfide bonds. They have a compact, globular fold (similar to other interleukins), stabilized by the 2 disulfide bonds. One half of the structure is dominated by a 4 alpha-helix bundle with a left-handed twist; the helices are anti-parallel, with 2 overhand connections, which fall into a 2-stranded anti-parallel beta-sheet. The fourth alpha helix is important to the biological activity of the molecule. Interleukin-6 (IL-6) is an important proinflammatory and immunoregulatory cytokine expressed by various cells. Interleukin-6 has been shown to inhibit the growth of early stage and to promote the proliferation of advanced stage melanoma cells in vitro.

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    图标文献和实验
    该产品被引用文献

    Cytokines of the IL6/GCSF/MGF family are glycoproteins of about 170 to 180 amino acid residues that contain four conserved cysteine residues involved in two disulfide bonds. They have a compact, globular fold (similar to other interleukins), stabilized by the 2 disulfide bonds. One half of the structure is dominated by a 4 alpha-helix bundle with a left-handed twist; the helices are anti-parallel, with 2 overhand connections, which fall into a 2-stranded anti-parallel beta-sheet. The fourth alpha helix is important to the biological activity of the molecule. Interleukin-6 (IL-6) is an important proinflammatory and immunoregulatory cytokine expressed by various cells. Interleukin-6 has been shown to inhibit the growth of early stage and to promote the proliferation of advanced stage melanoma cells in vitro.

    相关实验
    • 猴白细胞介素-6(IL-6)酶联免疫分析(ELISA)

      猴白细胞介素 - 6( IL- 6) 酶联免疫 分析( ELISA ) 试剂 盒使用说明书 本试剂仅供研究使用          目的:本试剂盒用于测定猴血清,血浆及相关液体样本中 白细胞介素-6(IL-6) 含量。 实验原理 :     本试剂盒应用 双抗体 夹心法测定 标本 中 猴白细胞介素 - 6( IL- 6) 水平。用纯化的 猴白细胞介素 - 6( IL- 6)抗体 包被微孔板,制成固相 抗 体,往包被 单抗 的微孔中依次

    • 白细胞介素IL-6

      白细胞介素 IL-6   IL-6主要产生细胞:单核细胞、巨噬细胞、成纤维细胞、T细胞、内皮细胞   IL-6氨基酸数目:186   IL-6分子质量(kDa):19-28   IL-6受体:CD126;CD130   IL-6主要生物学活性:刺激T细胞、B细胞、杂交瘤细胞和干细胞增殖;促进B细胞产生Ig;促进CTL、NK、干细胞和巨核细胞分化

    • 一份大鼠IL-6 ELISA说明书

      一、用途本试剂盒用于定量检测大鼠血清中的IL-6的浓度。二、原理本试剂盒采用双抗夹心ELISA法。抗大鼠IL-6单抗包被于酶标板上,大鼠标本中的IL-6会与单抗结合。加入生物素化的抗大鼠IL-6(二抗),它将与结合在单抗上的大鼠IL-6结合而形成免疫复合物,未结合的将被洗去。辣根过氧化物酶标记的Streptavidin 将与二抗的生物素结合,多余的物质会被洗掉。加入TMB显色。大鼠IL-6的浓度与OD(450nm)成正比。三、试剂盒组成酶标板(Coated Wells)48wellsAnti

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    文献支持
    Human IL-6
    ¥936 - 14080