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P01244 Recombinant Human OGG1/N-glycosylase/DNA lyase 细胞因子/蛋白
￥1092P01123 Recombinant Cynomolgus PD-1/CD279/PDCD1/Programmed cell death protein 1 细胞因子/蛋白
￥988P01197 Recombinant Human CD40/TNFRSF5/CD40L receptor 细胞因子/蛋白
￥988P00115 Recombinant Human/Mouse Fibroblast growth factor 8/FGF-8b/AIGF/HBGF-8 细胞因子/蛋白
￥1092P00415 Recombinant Human IL-18RAP 细胞因子/蛋白
￥468
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- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
50ug/1mg/500ug/10ug
| 规格： | 50ug | 产品价格： | ￥3640.0 |
|---|---|---|---|
| 规格： | 1mg | 产品价格： | ￥16896.0 |
| 规格： | 500ug | 产品价格： | ￥11808.0 |
| 规格： | 10ug | 产品价格： | ￥1217.0 |
Recombinant Human Interleukin-6 is produced by our E.coli expression system and the target gene encoding
Pro29-Met212 is expressed.
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Impact of Corticosteroids on the Proportions of Circulating Tfh Cell Subsets in Patients With Systemic Lupus Erythematous
成员:Minjing Mao, Shuqin Xu, Lin Lin, Danfeng Dong, Minghui Xue, Siwei He, Gang Cai
论文因子:5.058 发表期刊:Frontiers in Medicine pmid:35865165
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Blockade of PD-1 and TIM-3 Ameliorates CD8+ T Cell Exhaustion in a Mouse Model of Chronic Myeloid Leukemia
成员:Jin Ting, Gao Fei, Wang Li
论文因子:1.8 发表期刊:CELL BIOCHEMISTRY AND BIOPHYSICS pmid:38995531
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Effect of Baricitinib on the epithelial-mesenchymal transition of alveolar epithelial cells induced by IL-6
成员:Yiping Liu, Ming Hu, Guanzhi Fan, Nanshu Xing, Rong Zhang
论文因子:5.714 发表期刊:INTERNATIONAL IMMUNOPHARMACOLOGY pmid:35850052
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Cathepsin B-Responsive Programmed Brain Targeted Delivery System for Chemo-Immunotherapy Combination Therapy of Glioblastoma
成员:Shaoping Jiang, Wenpei Li, Jun Yang, Tian Zhang, Yuquan Zhang, Lin Xu, Bo Hu, Zhi Li, Huile Gao, Yuanyu Huang, Shaobo Ruan
论文因子:17.1 发表期刊:ACS Nano pmid:38358804
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Discovery of potent STAT3 inhibitors using structure-based virtual screening, molecular dynamic simulation, and biological evaluation
成员:Liu Weifeng, Chu Zhijie, Yang Cheng, Yang Tianbao, Yang Yanhui, Wu Haigang, Sun Junjun
论文因子:4.7 发表期刊:Frontiers in Oncology pmid:38023173
| 基本信息 | |
| 基因名 | |
| 别名 | Interleukin-6;IL-6;B-Cell Stimulatory Factor 2;BSF-2;CTL Differentiation Factor;CDF;Hybridoma Growth Factor;Interferon Beta-2;IFN-Beta-2;IL6;IFNB2 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 区间范围 | PVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLV KIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFK EFLQSSLRALRQM |
| 背景说明 | Cytokines of the IL6/GCSF/MGF family are glycoproteins of about 170 to 180 amino acid residues that contain four conserved cysteine residues involved in two disulfide bonds.They have a compact，globular fold (similar to other interleukins)，stabilized by the 2 disulfide bonds.One half of the structure is dominated by a 4 alpha-helix bundle with a left-handed twist; the helices are anti-parallel，with 2 overhand connections，which fall into a 2- stranded anti-parallel beta-sheet.The fourth alpha helix is important to the biological activity of the molecule.Interleukin-6 (IL-6) is an important proinflammatory and immunoregulatory cytokine expressed by various cells.Interleukin-6 has been shown to inhibit the growth of early stage and to promote the proliferation of advanced stage melanoma cells in vitro. |
| 来源 | E.coli |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/μg(1 EU/μg)as determined by LAL test. |
| 单位 | 支 |
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文献和实验【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Impact of Corticosteroids on the Proportions of Circulating Tfh Cell Subsets in Patients With Systemic Lupus Erythematous
成员:Minjing Mao, Shuqin Xu, Lin Lin, Danfeng Dong, Minghui Xue, Siwei He, Gang Cai
论文因子:5.058 发表期刊:Frontiers in Medicine pmid:35865165
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Blockade of PD-1 and TIM-3 Ameliorates CD8+ T Cell Exhaustion in a Mouse Model of Chronic Myeloid Leukemia
成员:Jin Ting, Gao Fei, Wang Li
论文因子:1.8 发表期刊:CELL BIOCHEMISTRY AND BIOPHYSICS pmid:38995531
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Effect of Baricitinib on the epithelial-mesenchymal transition of alveolar epithelial cells induced by IL-6
成员:Yiping Liu, Ming Hu, Guanzhi Fan, Nanshu Xing, Rong Zhang
论文因子:5.714 发表期刊:INTERNATIONAL IMMUNOPHARMACOLOGY pmid:35850052
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Cathepsin B-Responsive Programmed Brain Targeted Delivery System for Chemo-Immunotherapy Combination Therapy of Glioblastoma
成员:Shaoping Jiang, Wenpei Li, Jun Yang, Tian Zhang, Yuquan Zhang, Lin Xu, Bo Hu, Zhi Li, Huile Gao, Yuanyu Huang, Shaobo Ruan
论文因子:17.1 发表期刊:ACS Nano pmid:38358804
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Discovery of potent STAT3 inhibitors using structure-based virtual screening, molecular dynamic simulation, and biological evaluation
成员:Liu Weifeng, Chu Zhijie, Yang Cheng, Yang Tianbao, Yang Yanhui, Wu Haigang, Sun Junjun
论文因子:4.7 发表期刊:Frontiers in Oncology pmid:38023173
Secretion of Recombinant Human Insulin-Like Growth Factor I (IGF-I)
The development of efficient recombinant protein production processes can be a critical factor in whether or not a pharmaceutical therapeutic protein can enter human clinical trials and ultimately the marketplace. This is especially true
In this chapter we describe efficient procedures for the construction, expression and screening of comprehensive libraries of human Fab antibody fragments displayed on the surface of filamentous phage. Phagemid vectors are used for placing
我们知道，PeproTech的所有细胞因子和蛋白均为冻干粉，这使得运输非常便捷，只要常温即可。而且，细胞因子和蛋白冻干粉非常稳定，在-20℃或-80℃条件下可保存数年。冻干粉在使用前需进行溶解，然后以液体形式加到培养体系或注射入动物体内。溶解步骤非常关键，因溶解不好会导致细胞因子或蛋白的失活，这也是很多用户在实际使用中经常遇到的问题。 那么，应该如何进行正确的溶解呢？ 下面我们以Recombinant Human IL-4 (重组人IL-4，产品编号：200-04)的说明书为例
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