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- 2025年10月29日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
蛋白表达区间:Thr20-Cys352
- 保质期：
See instructions
- 英文名：
标签:C-6His
- 库存：
表达系统:Human Cells
- 供应商：
上海经科化学科技有限公司
- 规格：
10ug/50ug/500ug/1mg
| 规格： | 10ug | 产品价格： | ￥640.0 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ￥1760.0 |
| 规格： | 500ug | 产品价格： | ￥12320.0 |
| 规格： | 1mg | 产品价格： | ￥17600.0 |
- Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
- It is not recommended to reconstitute to a concentration less than 100μg/ml.
- Dissolve the lyophilized protein in distilled water.
- Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- The product is shipped at ambient temperature.
- Upon receipt, store it immediately at the temperature listed below.
- Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
- Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
- Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
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文献和实验CD14 is a cell surface glycoprotein that is preferentially expressed on monocytes/macrophages. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a pattern recognition receptor that binds lipopolysaccharides (LPS) and a variety of ligands derived from different microbial sources. The binding of CD14 with LPS is catalyzed by LPS binding protein (LBP). Toll like receptors have also been implicated in the transduction of CD14-LPS signals. Soluble CD14 can be released from the cell surface by phosphatidyinositolspecific phospholipase C and has been detected in serum and body fluids. High concentrations of soluble CD14 have been shown to inhibit LPS mediated responses. However, soluble CD14 can also potentiate LPS response in cells that do not express cell surface CD14.
CD14 分子 CD14 常用单克隆抗体或代号：Mo2,UCHM1,LeuM3,MY4 主要表达细胞：M,G,DC,LHC [M] 分子质量(kDa)和结构：gp55(GPI连接) 功 能：LPS/LBP复合体受体 CD14 Aka lipopolysaccharide (LPS) receptor, endotoxin receptor Binding
Dendritic Cell Generation from Highly Purified CD14+Monocytes
lineage with several subsets, functions, and maturational stages. Although it is generally accepted that human DC derive from hematopoietic progenitor cells (2 -9 ), it is not clear at present whether DC cells and their precursors represent a separate
Calcitriol (1α, 25-dihydroxyvitamin D3 ) induces the expression of CD14 in mononuclear phagocytes. The mechanisms accounting for this have been unclear since the promoter of CD14 does not contain a canonical vitamin D response element (VDRE
技术资料
