Cyclin-Dependent Kinase 9 (CDK

yb311733 产品详细信息
Cyclin-Dependent Kinase 9 (CDK9) (N-Term) 抗体
anti-Cyclin-Dependent Kinase 9 (CDK9) (N-Term) antibody
抗原
Cyclin-Dependent Kinase 9 (CDK9)
别名 CDK9, CG5179, Dmel\\CG5179, P-TEF, P-TEFb, PTefb, cdk9, c-2k, cdc2l4, ctk1, pitalre, tak, C-2k, CDC2L4, CTK1, PITALRE, TAK, wu:fb22e09, wu:fc06c02
抗原表位
其他选择 N-Term
适用
其他选择 犬, 小鼠, 大鼠, 斑马鱼, 牛, 猪, 非洲爪蟾, 人, 小鸡
宿主
其他选择 兔
克隆类型
多克隆
标记
其他选择 非结合性
应用范围
其他选择 Western Blotting (WB)
Pubmed 找到1个引用
规格 100 μg
发货至 中国 (更改)
发货时间 9至12个工作日
产品细节Cyclin-Dependent Kinase 9 (CDK9) (N-Term) 抗体
免疫原 Synthetic peptide directed towards the N terminal of human CDK9
序列 PFCDEVSKYE KLAKIGQGTF GEVFKARHRK TGQKVALKKV LMENEKEGFP
预测反应 Chicken : 100 %, Dog : 100 %, Human : 100 %, African clawed frog : 90 %, Bovine : 90 %, Mouse : 90 %, Pig : 90 %, Rat : 90 %, Zebrafish : 90 %
产品特性 This is a rabbit polyclonal antibody against CDK9. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Protein A purified
目标详细情况 Cyclin-Dependent Kinase 9 (CDK9) (N-Term) 抗体
别名 CDK9
背景 CDK9 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.
分子量 43 kDa
基因ID 1025
NCBI登录号 NP_001252, NM_001261
UniProt P50750
研究领域 Cell Cycle
使用细节Cyclin-Dependent Kinase 9 (CDK9) (N-Term) 抗体
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明
Antigen size: 372 AA
限制 仅限研究用
贮存及处理 Cyclin-Dependent Kinase 9 (CDK9) (N-Term) 抗体
状态 Lyophilized
溶解方式 Add 100 µL of distilled water.
浓度 1 mg/mL
缓冲液 PBS buffer with 2 % sucrose
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For longer periods of storage, store at -20 °C
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