PSME3 (PSME3) (C-Term) 抗体

yb310781 产品详细信息
PSME3 (PSME3) (C-Term) 抗体
anti-PSME3 (PSME3) (C-Term) antibody
抗原
PSME3 (PSME3)
别名 AA410043, AU020960, Ki, PA28gamma, REGgamma, pa28g, Ab2-371, PA28-gamma, PA28G, REG-GAMMA, psme3b
抗原表位
其他选择 C-Term
适用
其他选择 小鼠, 大鼠, 非洲爪蟾, 猪, 牛, 犬, 人, 小鸡
宿主
其他选择 兔
克隆类型
多克隆
标记
其他选择 非结合性
应用范围
其他选择 Western Blotting (WB)
Pubmed 找到1个引用
规格 100 μg
发货至 中国 (更改)
发货时间 9至12个工作日
产品细节 PSME3 (PSME3) (C-Term) 抗体
免疫原 Synthetic peptide directed towards the C terminal of human PSME3
序列 TVTEIDEKEY ISLRLIISEL RNQYVTLHDM ILKNIEKIKR PRSSNAETLY
预测反应 African clawed frog : 100 %, Bovine : 100 %, Chicken : 100 %, Dog : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %, Zebrafish : 70 %
产品特性 This is a rabbit polyclonal antibody against PSME3. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Protein A purified
目标详细情况 PSME3 (PSME3) (C-Term) 抗体
别名 PSME3
背景 The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. PSME3 is the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring. Two transcript variants encoding different isoforms have been identified.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring. Two transcript variants encoding different isoforms have been identified.
分子量 29 kDa
基因ID 10197
NCBI登录号 NP_005780, NM_005789
UniProt P61289
研究领域 Immunology, Proteolysis / Ubiquitin, Proteasome
使用细节PSME3 (PSME3) (C-Term) 抗体
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明
Antigen size: 254 AA
限制 仅限研究用
贮存及处理 PSME3 (PSME3) (C-Term) 抗体
状态 Lyophilized
溶解方式 Add 100 µL of distilled water.
浓度 1 mg/mL
缓冲液 PBS buffer with 2 % sucrose
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For longer periods of storage, store at -20 °C
yb-5229R phospho-CDKN1B (Thr187)磷酸化P27抗体/周期素依赖激酶抑制剂抗体 浓度1mg/ml
yb-5236R phospho-CDKN1B (Ser178)磷酸化P27抗体/周期素依赖激酶抑制剂抗体 浓度1mg/ml
yb-5237R phospho-CDKN1A (Thr145)磷酸化p21蛋白抗体 浓度1mg/ml
yb-5238R phospho-CDKN1A (Thr57)磷酸化p21蛋白抗体 浓度1mg/ml
yb-15304R c8orf848号染色体开放阅读框84抗体 浓度1mg/ml
yb-5239R phospho-CDKN1A (Ser146)磷酸化p21蛋白抗体 浓度1mg/ml
yb-3060R Phospho-CEBP alpha (Ser21)磷酸化转录调节因子CEBP α 抗体 浓度1mg/ml
yb-2683R CLEC2DCLEC2D蛋白抗体 浓度1mg/ml
yb-8185R CRELD2富含半胱氨酸与表皮生长因子样蛋白2抗体 浓度1mg/ml
yb-8186R CRYZL1醌氧化还原酶样蛋白1抗体 浓度1mg/ml
yb-8180R COMMD9铜代谢结构域蛋白9抗体 浓度1mg/ml
yb-7734R CAPD3浓缩素2复合亚基D3抗体 浓度1mg/ml
yb-5246R phospho-Cdc6 (Ser54)磷酸化细胞分裂周期蛋白6抗体 浓度1mg/ml
yb-5247R Phospho-cdc2 (Ser39)磷酸化周期素依赖激酶2抗体 浓度1mg/ml
yb-6025R CA12碳酸酐酶12抗体 浓度1mg/ml
yb-3813R CDC34B泛素载体蛋白R2抗体 浓度1mg/ml
yb-6027R CADM3细胞粘附分子3抗体 浓度1mg/ml
yb-2386R CD47整合素相关蛋白CD47 浓度1mg/ml
yb-3743R phospho-CK8 (Ser23)磷酸化细胞角蛋白8抗体 浓度1mg/ml
yb-3758R Calbindin钙结合蛋白D28K抗体 浓度1mg/ml
yb-3738R phospho-Crkl(Tyr251)磷酸化接头蛋白CrkL抗体 浓度1mg/ml