Ring Finger Protein 128 (RNF12

yb310450 产品详细信息
Ring Finger Protein 128 (RNF128) (C-Term) 抗体
anti-Ring Finger Protein 128 (RNF128) (C-Term) antibody anti-Ring Finger Protein 128 (RNF128) (C-Term) antibody (2)
抗原
Ring Finger Protein 128 (RNF128)
别名 rnf128, wu:fb57h05, zgc:77843, 1300002C13Rik, AI987883, GRAIL, Greul1, RGD1566282, grail, greul1
抗原表位
其他选择 C-Term
适用
其他选择 小鼠, 大鼠, 犬, 牛, 人
宿主
其他选择 兔
克隆类型
多克隆
标记
其他选择 非结合性
应用范围
其他选择 Western Blotting (WB)
Pubmed 找到1个引用
规格 100 μg
发货至 中国 (更改)
发货时间 9至12个工作日
产品细节Ring Finger Protein 128 (RNF128) (C-Term) 抗体
免疫原 Synthetic peptide directed towards the C terminal of human RNF128
序列 LEEHVQSTNE SLQLVNHEAN SVAVDVIPHV DNPTFEEDET PNQETAVREI
预测反应 Human : 100 %, Dog : 90 %, Mouse : 90 %, Rat : 90 %
产品特性 This is a rabbit polyclonal antibody against RNF128. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Protein A purified
目标详细情况 Ring Finger Protein 128 (RNF128) (C-Term) 抗体
别名 RNF128
背景 RNF128 is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of RNF128 in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of RNF128 was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype.The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
分子量 47 kDa
基因ID 79589
NCBI登录号 NM_194463, NP_919445
UniProt Q8TEB7
研究领域 Proteolysis / Ubiquitin
使用细节 Ring Finger Protein 128 (RNF128) (C-Term) 抗体
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明
Antigen size: 428 AA
限制 仅限研究用
贮存及处理 Ring Finger Protein 128 (RNF128) (C-Term) 抗体
状态 Lyophilized
溶解方式 Add 100 µL of distilled water.
浓度 1 mg/mL
缓冲液 PBS buffer with 2 % sucrose
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For longer periods of storage, store at -20 °C
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