CD19 Molecule (CD19) 抗体 (PE)

CD19 Molecule (CD19) 抗体 (PE)抗原
CD19 Molecule (CD19)
别名 CD19, AW495831, B4, CVID3
适用
其他选择 人
宿主
其他选择 小鼠
克隆类型 (克隆位点)
单克隆 (LT19)
标记
其他选择 This CD19 antibody is conjugated to PE
应用范围
其他选择 流式细胞分析技术（FACS）
Pubmed 8个引用可参考
规格 100 tests
发货至 中国 (更改)
发货时间 23至29个工作日
产品编号 yb94016
CD19抗体: 产品细节 CD19 Molecule (CD19) 抗体 (PE)
免疫原 Daudi human Burkitt lymphoma cell line
克隆位点 LT19
亚型 IgG1
特异性 The antibody LT19 reacts with CD19 (B4), a 95 kDa type I transmembrane glycoprotein (immunoglobulin superfamily) expressed on B lymphocytes and follicular dendritic cells, it is lost on plasma cells.
产品特性 The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.
CD19:目标详细情况CD19 Molecule (CD19) 抗体 (PE)
别名 CD19
背景 CD19 is a transmembrane glycoprotein of Ig superfamily expressed by B cells from the time of heavy chain rearrangement until plasma cell differentiation. It forms a tetrameric complex with CD21 (complement receptor type 2), CD81 (TAPA-1) and Leu13. Together with BCR (B cell antigen receptor), this complex signals to decrease B cell treshold for activation by the antigen. Besides being signal-amplifying coreceptor for BCR, CD19 can also signal independently of BCR coligation and it turns out to be a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.
研究领域 Stem Cells, Hematopoietic Progenitors, Hematopoietic Stem Cells, Adaptive Immunity, CD Antigens, Surface Receptors of Immune Cells
使用细节 CD19 Molecule (CD19) 抗体 (PE)
应用备注 The reagent is designed for Flow Cytometry analysis of human blood cells using 20 µL reagent / 100 µL of whole blood or 10^6 cells in a suspension. The content of a vial (2 mL) is sufficient for 100 tests.

Working concentrations should be determined by the investigator.
限制 仅限研究用
贮存及处理 CD19 Molecule (CD19) 抗体 (PE)
溶解方式 No reconstitution is necessary.
缓冲液 The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
储存液 Sodium azide
注意事项 WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
注意事项 Do not freeze.
Avoid prolonged exposure to light.
储存条件 4 °C
储存方法 Store in the dark at 2-8 °C. Do not use after expiration date stamped on vial label. Short-term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user.