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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20℃
- 克隆性:
单克隆
- 抗体名:
Estrogen Receptor 1 (ESR1) 抗体
- 规格:
0.1ml/0.2ml
Estrogen Receptor 1 (ESR1)
别名
ACTGP1, ACT1GP1, HY-psi-gamma-AC6, ER[b]2, ER[b]a, zfER[b]2, zfER-beta2, XER, era, esr, esra, nr3a1, ERbeta, xesr-1, ERalpha, xlERalpha1, xlERalpha2, LOC398733, LOC398734, 2610524P08Rik, 9130407C09Rik ... show more
适用
其他选择 人
宿主
其他选择 小鼠
克隆类型 (克隆位点)
单克隆 (1D5)
标记
其他选择 非结合性
应用范围
其他选择 Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), 免疫组织化学石蜡技术(IHC-P)
Pubmed 4个引用可参考
规格 1 mL
发货至 中国 (更改)
发货时间 29至35个工作日
产品编号 yb114680
产品细节 Estrogen Receptor 1 (ESR1) 抗体
免疫原 Recombinant human estrogen receptor protein.
克隆位点 1D5
亚型 IgG1
特异性 This antibody is specific to estrogen receptor, which is associated with superior prognosis and a better response to endocrine therapy.
Cellular Localization: Nuclear
纯化方法 Supernatant
目标详细情况 Estrogen Receptor 1 (ESR1) 抗体
别名 Estrogen Receptor alpha
背景 The nuclei of the estrogen receptor positive cells stain very strongly with this antibody, without any staining in the cytoplasm. However, on cryostat sections a positive staining of estrogen receptor in the nucleus as well as cytoplasm can be seen.Synonyms: ER alpha, ESR, ESR1, Estradiol receptor, NR3A1, Nuclear receptor subfamily 3 group A member 1
基因ID 2099
NCBI登录号 NP_000116
UniProt P03372
研究领域 Cancer, Endocrine system, Transcription Factors, Hormones, Receptors
使用细节 Estrogen Receptor 1 (ESR1) 抗体
应用备注 Western Blotting: 1: 50 to 1: 100. Immunohistochemistry on frozen and paraffin embedded sections: diluted of 1: 25 to 1: 50 inan ABC method (30 minutes at room temperature)Recommended Positive Control: Breast carcinoma
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
贮存及处理Estrogen Receptor 1 (ESR1) 抗体
状态 Liquid
缓冲液 10 mM citrate buffer, pH 6.0 - containing sodium azide as preservative.
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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文献和实验。 4. 牛碱性磷酸酶(Cow calf alkaline phosphalase,CAP) 该抗体可检测正常的成骨细胞,小肠细胞,前列腺上皮细胞,全身含有CAP的细胞。但临床常用它来检测骨肿瘤及前列腺肿瘤CAP的含量,该抗体不需作任何处理,适合于各种切片。 5.雌激素受体,(Estrogen receptor ,ER) ER是一种具有特定功能的酸性蛋白,是传递激素信息的一种特异性的物质。经研究发现,这种物质存在于癌细胞的细胞核中,如乳腺癌、子宫内膜腺癌,宫颈
浅析染色质免疫沉淀(ChIP)技术在 DNA 与蛋白质相互作用研究中的重要性
. Apoptosis, 2008. 13(7): p. 929-37. [15] Metivier, R., et al., Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter. Cell, 2003. 115(6): p. 751-63. [16] Shi, H., et al., TLR4 links innate
独体—基于纤连蛋白类型Ⅲ结构域框架的抗体模拟 Akiko Koide and Shohei Koide
conformational changes byusing designer binding proteins: application to the estrogen receptor. Proc. Natl. Acad. ScL USA 99? 1253-1258. 11. Sidhu, S. S. , Lowman, H. B. , Cunningham, B. C. , and Wells, J. A. (2000) Phage display
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