Estrogen Receptor 1 (ESR1) Rab

ProductName：Estrogen Receptor 1 (ESR1) Rabbit Monoclonal Antibody
description：ER alpha Antibody
symbol：ESR1
synonyms：ER; Era; ESR; ESR1; ESRA; NR3A1
locusid：2099
Concentration：lot specific
sub_category：Primary Antibodies
uniprot_id：P03372
Applications：ChIP, FC, ICC/IF, IHC, WB
CNdelivery：2周
RecommendDilution：WB 1:500~1:2000 IHC 1:50~1:100 ICC/IF 1:50~1:100 ChIP 5 ?g/30 ?g FC 1:30
Reactivity：Human, Mouse, Rat, Dog
Immunogen：A synthesized peptide derived from human ER alpha
Purification：Affinity-chromatography
Conjugation：Unconjugated
ProteinFamilies：null
ProteinPathways：null
GeneName：estrogen receptor 1
Background：ER (estrogen receptor 1) a member of the steroid receptor superfamily, contains highly conserved DNA binding (DBD) and ligand binding domains (LBD). Through its estrogen-independent and estrogen-dependent activation domains (AF-1 and AF-2, respectively), ER regulates transcription by recruiting coactivator proteins and interacting with general transcriptional machinery. Phosphorylation provides an important mechanism to regulate ER activity. ER is phosphorylated on multiple sites.
Buffer：Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
isotypes_filter：IgG
predicted_size：60kDa