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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20℃
- 克隆性:
单克隆
- 抗体名:
BCL2-Related Protein A1 (BCL2A1) (C-Term) 抗体
- 规格:
0.1ml/0.2ml
BCL2-Related Protein A1 (BCL2A1)
别名 BCL2A1, A1, BB218357, Bcl2a1, Bfl-1, Hbpa1, ACC-1, ACC-2, BCL2L5, BFL1, GRS, HBPA1, Bcl2a1d
抗原表位
其他选择 C-Term
适用
其他选择 大鼠, 小鼠, 牛, 犬, 猪, 人
宿主
其他选择 兔
克隆类型
多克隆
标记
其他选择 非结合性
应用范围
其他选择 Western Blotting (WB)
Pubmed 找到1个引用
规格 50 μg
发货至 中国 (更改)
发货时间 9至12个工作日
产品编号 yb184209
产品细节 BCL2-Related Protein A1 (BCL2A1) (C-Term) 抗体
免疫原 Synthetic peptide directed towards the C terminal of human BCL2A1
序列 FIMNNTGEWI RQNGGWENGF VKKFEPKSGW MTFLEVTGKI CEMLSLLKQY
预测反应 Dog : 90 %, Pig : 80 %, Rat : 70 %
产品特性 This is a rabbit polyclonal antibody against BCL2A1. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Affinity Purified
目标详细情况 BCL2-Related Protein A1 (BCL2A1) (C-Term) 抗体
别名 BCL2A1
背景 BCL2A1s a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and has been shown to be up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival.
分子量 20 kDa
基因ID 597
NCBI登录号 NM_004049, NP_004040
UniProt Q16548
使用细节 BCL2-Related Protein A1 (BCL2A1) (C-Term) 抗体
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明
Antigen size: 175 AA
限制 仅限研究用
贮存及处理 BCL2-Related Protein A1 (BCL2A1) (C-Term) 抗体
状态 Lyophilized
溶解方式 Add 50 µL of distilled water.
浓度 1 mg/mL
缓冲液 PBS buffer with 2 % sucrose
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For longer periods of storage, store at -20 °C
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