相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 保存条件:
-20℃
- 克隆性:
单克隆
- 抗体名:
PARP (Cleavage Site) 抗体
- 规格:
0.1ml/0.2ml
PARP (Cleavage Site) 抗体
anti-PARP (Cleavage Site) antibody
抗原
PARP
别名
ADPRT, ADPRT 1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1, adprt1, padprt-1, parp, ppol, 5830444G22Rik, AI893648, Adprp, Adprt1, C80510, parp-1, sPARP-1, BEST:LD21673, CG17685, CG17696, CG17718, CG4 ... show more
抗原表位
其他选择 Cleavage Site
适用
其他选择 人
宿主
其他选择 兔
克隆类型
多克隆
应用范围
其他选择 Western Blotting (WB)
Pubmed 找到1个引用
规格 100 μg
发货至 中国 (更改)
发货时间 24至29个工作日
产品细节 PARP (Cleavage Site) 抗体
免疫原 Synthetic peptide corresponding to caspase cleavage site in human PARP
亚型 IgG
纯化方法 Affinity purified
目标详细情况 PARP (Cleavage Site) 抗体
背景 PARP, a 116 kDa nuclear poly (ADP-ribose) polymerase, is a highly conserved nuclear enzyme implicated in DNA repair and in the apoptosis response of cells. This protein can be cleaved by many caspases in vitro and is one of the main cleavage targets of caspase-3 in vivo. The cleavage occurs between ASP214 and Gly 215, which separates PARP's N-terminal DNA binding domain (24 kDa) from its C-terminal catalytic domain (89 kDa). It has been shown that cleavage of PARP facilitates cellular disassembly and inhibition of PARP cleavage attenuates apoptosis in vitro.
基因ID 142
研究领域 Chromatin and Nuclear Signaling, DNA/RNA, Enzymes, Metabolism
使用细节 PARP (Cleavage Site) 抗体
应用备注 Western blot analysis (1-4 µg/mL).
However the optimal concentrations should be determined individually.
限制 仅限研究用
贮存及处理 PARP (Cleavage Site) 抗体
状态 Liquid
浓度 0.2 mg/mL
缓冲液 PBS containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal
储存液 Thimerosal (Merthiolate)
注意事项 This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
储存条件 -20 °C/-80 °C
储存方法 For long-term storage, aliquot and freeze at -70 °C.
有效期 12 months
yb-10154R Phospho-ELk1(Ser383)磷酸化细胞转录因子ELK1抗体 浓度1mg/ml
yb-12341R ETV2ETS相关蛋白71抗体 浓度1mg/ml
yb-12347R EDA外胚层发育不良蛋白1抗体 浓度1mg/ml
yb-13114R ETV3LETV3L蛋白抗体 浓度1mg/ml
yb-2571R EphB6酪氨酸蛋白激酶受体B6抗体 浓度1mg/ml
yb-2880R LPA1溶血磷脂酸受体蛋白1抗体 浓度1mg/ml
yb-2881R LPA2溶血磷脂酸受体蛋白2抗体 浓度1mg/ml
yb-2882R LPA3溶血磷脂酸受体蛋白3抗体 浓度1mg/ml
yb-2883R EDG6内皮细胞的分化蛋白6抗体 浓度1mg/ml
yb-6005R EXTL2外生性骨疣样蛋白2抗体 浓度1mg/ml
yb-5334R phospho-EIF4EBP1 (Ser100)磷酸化eIF4E结合蛋白抗体 浓度1mg/ml
yb-5337R phospho-EIF4EBP1(Ser111)磷酸化eIF4E结合蛋白抗体 浓度1mg/ml
yb-3615R ESM1内皮细胞特异性分子1抗体 浓度1mg/ml
yb-3841R eIF3F真核翻译起始因子3F抗体 浓度1mg/ml
yb-3842R eIF3H真核翻译起始因子3H抗体 浓度1mg/ml
yb-3843R eIF4G真核翻译起始因子4G抗体 浓度1mg/ml
yb-3844R eIF6β4整合素结合蛋白抗体 浓度1mg/ml
yb-9807R ECRG4食道癌相关基因4蛋白抗体 浓度1mg/ml
yb-2343R EPO红细胞生成素抗体 浓度1mg/ml
yb-3880R EPHX2胞浆环氧化物水解酶抗体 浓度1mg/ml
yb-6213R Estrogen Related Receptor gamma雌激素受体相关蛋白3抗体 浓度1mg/ml
yb-6212R Estrogen Related Receptor beta雌激素相关受体β抗体 浓度1mg/ml
yb-6264R EMP2上皮细胞膜蛋白2抗体 浓度1mg/ml
yb-2947R ERG25甲基固醇羟化酶单加氧酶1抗体 浓度1mg/ml
yb-6527R EST1A端粒酶结合蛋白EST1A抗体 浓度1mg/ml
yb-6528R EZH1组蛋白赖氨酸N-甲基EZH1抗体 浓度1mg/ml
yb-6532R Epithelial Stromal Interaction 1上皮间质相互作用蛋白1抗体 浓度1mg/ml
yb-6533R EIG121雌激素诱导基因121蛋白抗体 浓度1mg/ml
yb-5884R Endomucin内皮粘蛋白EMCN抗体 浓度1mg/ml
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
- 作者
- 内容
- 询问日期
文献和实验PARP Cleavage as a Means of Assessing Apoptosis
Although cell death is often seen as a pathological process, there are classically two types of cell death in biological systems, namely necrosis (accidental cell death) and apoptosis (programmed cell death). Although it was recognized
PARP Cleavage and Caspase Activity to Assess Chemosensitivity
of cysteine proteases, known as caspases. In normal conditions, all the caspases exist as inactive procaspases; they require proteolytic cleavage for activation. A variety of methods are currently used to detect procaspases and caspases and their activity
Small-Molecule Collection and High-Throughput Colorimetric Assay to Identify PARP1 Inhibitors
to disrupt the DNA-dependent PARP1 protein activation pathway and were based on a competition with NAD for a binding site on PARP molecule and, therefore, on disruption of PARP-mediated enzymatic reaction. This limitation resulted in a discovery of mainly
技术资料暂无技术资料 索取技术资料






