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- 文献和实验
- 技术资料
- 保存条件:
-20℃
- 克隆性:
单克隆
- 抗体名:
Recoverin (RCVRN) (C-Term) 抗体
- 规格:
0.1ml/0.2ml
Recoverin (RCVRN) (C-Term) 抗体抗原
Recoverin (RCVRN)
别名 fk53a03, zgc:73121, wu:fk53a03, rcv1, recoverin, RCV1, zgc:114180, reco, rcvrn, Rcv1, CAR, S-modulin
抗原表位
其他选择 C-Term
适用
其他选择 大鼠, 牛, 犬, 人
宿主
其他选择 兔
克隆类型
多克隆
标记
其他选择 非结合性
应用范围
其他选择 Western Blotting (WB)
Pubmed 找到1个引用
规格 50 μg
发货至 中国 (更改)
发货时间 9至12个工作日
产品编号 yb183626
产品细节 Recoverin (RCVRN) (C-Term) 抗体
免疫原 Synthetic peptide directed towards the C terminal of human RCV1
序列 KMITPEDVKL LPDDENTPEK RAEKIWKYFG KNDDDKLTEK EFIEGTLANK
预测反应 Human :100 %, Bovine :80 %, American bullfrog :80 %, Leptotrichia goodfellowii F0264 :80 %, Rat :80 %, Dog :70 %,
产品特性 This is a rabbit polyclonal antibody against RCV1. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Affinity Purified
目标详细情况 Recoverin (RCVRN) (C-Term) 抗体
别名 RCV1
背景 RCV1 is a member of the recoverin family of neuronal calcium sensors. RCV1 contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy.The protein encoded by this gene contains four calcium-binding EF-hand domains and belongs to the recoverin family of neuronal calcium sensors. Recoverin may prolong the termination of the phototransduction cascade by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy, an autoimmune disease of the retina caused by a tumor in another tissue.
分子量 23 kDa
基因ID 5957
NCBI登录号 NP_002894, NM_002903
UniProt Q53XL0
使用细节 Recoverin (RCVRN) (C-Term) 抗体
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明
Antigen size: 200 AA
限制 仅限研究用
贮存及处理 Recoverin (RCVRN) (C-Term) 抗体
状态 Lyophilized
溶解方式 Add 50 µL of distilled water.
浓度 1 mg/mL
缓冲液 PBS buffer with 2 % sucrose
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For longer periods of storage, store at -20 °C
Recoverin (RCVRN)
别名 fk53a03, zgc:73121, wu:fk53a03, rcv1, recoverin, RCV1, zgc:114180, reco, rcvrn, Rcv1, CAR, S-modulin
抗原表位
其他选择 C-Term
适用
其他选择 大鼠, 牛, 犬, 人
宿主
其他选择 兔
克隆类型
多克隆
标记
其他选择 非结合性
应用范围
其他选择 Western Blotting (WB)
Pubmed 找到1个引用
规格 50 μg
发货至 中国 (更改)
发货时间 9至12个工作日
产品编号 yb183626
产品细节 Recoverin (RCVRN) (C-Term) 抗体
免疫原 Synthetic peptide directed towards the C terminal of human RCV1
序列 KMITPEDVKL LPDDENTPEK RAEKIWKYFG KNDDDKLTEK EFIEGTLANK
预测反应 Human :100 %, Bovine :80 %, American bullfrog :80 %, Leptotrichia goodfellowii F0264 :80 %, Rat :80 %, Dog :70 %,
产品特性 This is a rabbit polyclonal antibody against RCV1. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Affinity Purified
目标详细情况 Recoverin (RCVRN) (C-Term) 抗体
别名 RCV1
背景 RCV1 is a member of the recoverin family of neuronal calcium sensors. RCV1 contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy.The protein encoded by this gene contains four calcium-binding EF-hand domains and belongs to the recoverin family of neuronal calcium sensors. Recoverin may prolong the termination of the phototransduction cascade by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy, an autoimmune disease of the retina caused by a tumor in another tissue.
分子量 23 kDa
基因ID 5957
NCBI登录号 NP_002894, NM_002903
UniProt Q53XL0
使用细节 Recoverin (RCVRN) (C-Term) 抗体
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明
Antigen size: 200 AA
限制 仅限研究用
贮存及处理 Recoverin (RCVRN) (C-Term) 抗体
状态 Lyophilized
溶解方式 Add 50 µL of distilled water.
浓度 1 mg/mL
缓冲液 PBS buffer with 2 % sucrose
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For longer periods of storage, store at -20 °C
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文献和实验相关实验
因子的C-term,做成融合蛋白。刺激细胞之后,对细胞进行化学交联,并破碎细胞以及基因组DNA,然后用anti-FLAG抗体作免疫沉淀,将转录因子沉淀下来。最后分析这些转录因子所结合的DNA片段序列,从而找到该转录因子的在基因组上的识别序列,也就找到了该转录因子的作用基因。 荧光素酶做报告基因模式小鼠,一般是为了做活体成像实验。比如在一个细胞因子启动子下面放置荧光素酶基因。免疫 小鼠之后,有些细胞或器官表达该细胞因子同时表达荧光素酶。通过注射荧光素酶底物可以检测荧光在小鼠体内的分布,从而得出该细胞
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Recoverin (RCVRN) (C-Term) 抗体
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