Vascular Cell Adhesion Molecule 1 (VCAM1) 抗体

Vascular Cell Adhesion Molecul

e 1 (VCAM1) 抗体
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  • 询价
  • 钰博生物
  • 进口/国产
  • yb135074
  • 2025年07月13日
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    • 详细信息
    • 技术资料
    • 保存条件

      -20℃

    • 克隆性

      单克隆

    • 抗体名

      Vascular Cell Adhesion Molecule 1 (VCAM1) 抗体

    • 规格

      0.1ml/0.2ml

    yb135074 产品详细信息
    Vascular Cell Adhesion Molecule 1 (VCAM1) 抗体
    anti-Vascular Cell Adhesion Molecule 1 (VCAM1) antibody
    抗原
    Vascular Cell Adhesion Molecule 1 (VCAM1)
    别名 fi76d06, wu:fi76d06, zgc:158875, VCAM1, CD106, INCAM-100, Vcam-1, VCAM1B
    适用
    其他选择 小鼠
    宿主
    其他选择 大鼠
    克隆类型 (克隆位点)
    单克隆 (M-K-2)
    标记
    其他选择 非结合性
    应用范围
    其他选择 流式细胞分析技术(FACS), 免疫组织化学(IHC), 免疫沉淀(IP)
    Pubmed 2个引用可参考
    规格 0.5 mg
    发货至 中国 (更改)
    产品细节Vascular Cell Adhesion Molecule 1 (VCAM1) 抗体
    克隆位点 M-K-2
    亚型 IgG1
    产品特性 The antibody detects: CD106/VCAM-1 (approx. Mr 100 kDa)
    The M/K-2 monoclonal antibody immunoprecipitates a peptide that gives a single band on SDS-PAGE gels with an apparent Mr of approx. 100 kDa under reducing conditions and 92 kDa under nonreducing conditions.
    内毒素水平 Low Endotoxin
    目标详细情况 Vascular Cell Adhesion Molecule 1 (VCAM1) 抗体
    别名 CD106/VCAM-1
    背景 VCAM-1 is an adhesion molecule and a major mediator of the inflammatory response. It is expressed on activated microvascular endothelial cells in response to signals arising from immune responses in infection, graft rejection, tumor recognition and killing. The complementary binding ligand for VCAM-1 is VLA-4/CD49d. In addition to VCAM-1, VLA-4 also recognizes the extracellular matrix molecule fibronectin. This pairing of VCAM-1 and VLA-4 is able to provide a second signal (i.e., non-antigen specific) for T cell stimulation, such as that seen in transplantation. The monoclonal antibody MK-2 has been used in transplant studies to suppress cardiac rejection and induce long-term cardiac graft survival. In addition to inflammatory responses, VCAM-1 has a significant role in hemopoiesis through its ability to retain lymphocyte and myeloid precursors on stromal cells in the marrow and lymphoid organs. CD106/VCAM-1 exists as an integral membrane protein.
    使用细节 Vascular Cell Adhesion Molecule 1 (VCAM1) 抗体
    应用备注 Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
    样本量 1 mL
    限制 仅限研究用
    贮存及处理 Vascular Cell Adhesion Molecule 1 (VCAM1) 抗体
    缓冲液 Product is supplied as 0.5 mg purified immunoglobulin in 1.0 mL of PBS.
    储存液 Azide free
    注意事项 Each reagent is stable for the period shown on the bottle label if stored as directed.
    储存条件 -20 °C
    储存方法 Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
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