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- 详细信息
- 技术资料
- 保存条件:
-20℃
- 克隆性:
单克隆
- 抗体名:
Vascular Cell Adhesion Molecule 1 (VCAM1) 抗体
- 规格:
0.1ml/0.2ml
yb135074 产品详细信息
Vascular Cell Adhesion Molecule 1 (VCAM1) 抗体
anti-Vascular Cell Adhesion Molecule 1 (VCAM1) antibody
抗原
Vascular Cell Adhesion Molecule 1 (VCAM1)
别名 fi76d06, wu:fi76d06, zgc:158875, VCAM1, CD106, INCAM-100, Vcam-1, VCAM1B
适用
其他选择 小鼠
宿主
其他选择 大鼠
克隆类型 (克隆位点)
单克隆 (M-K-2)
标记
其他选择 非结合性
应用范围
其他选择 流式细胞分析技术(FACS), 免疫组织化学(IHC), 免疫沉淀(IP)
Pubmed 2个引用可参考
规格 0.5 mg
发货至 中国 (更改)
产品细节Vascular Cell Adhesion Molecule 1 (VCAM1) 抗体
克隆位点 M-K-2
亚型 IgG1
产品特性 The antibody detects: CD106/VCAM-1 (approx. Mr 100 kDa)
The M/K-2 monoclonal antibody immunoprecipitates a peptide that gives a single band on SDS-PAGE gels with an apparent Mr of approx. 100 kDa under reducing conditions and 92 kDa under nonreducing conditions.
内毒素水平 Low Endotoxin
目标详细情况 Vascular Cell Adhesion Molecule 1 (VCAM1) 抗体
别名 CD106/VCAM-1
背景 VCAM-1 is an adhesion molecule and a major mediator of the inflammatory response. It is expressed on activated microvascular endothelial cells in response to signals arising from immune responses in infection, graft rejection, tumor recognition and killing. The complementary binding ligand for VCAM-1 is VLA-4/CD49d. In addition to VCAM-1, VLA-4 also recognizes the extracellular matrix molecule fibronectin. This pairing of VCAM-1 and VLA-4 is able to provide a second signal (i.e., non-antigen specific) for T cell stimulation, such as that seen in transplantation. The monoclonal antibody MK-2 has been used in transplant studies to suppress cardiac rejection and induce long-term cardiac graft survival. In addition to inflammatory responses, VCAM-1 has a significant role in hemopoiesis through its ability to retain lymphocyte and myeloid precursors on stromal cells in the marrow and lymphoid organs. CD106/VCAM-1 exists as an integral membrane protein.
使用细节 Vascular Cell Adhesion Molecule 1 (VCAM1) 抗体
应用备注 Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
样本量 1 mL
限制 仅限研究用
贮存及处理 Vascular Cell Adhesion Molecule 1 (VCAM1) 抗体
缓冲液 Product is supplied as 0.5 mg purified immunoglobulin in 1.0 mL of PBS.
储存液 Azide free
注意事项 Each reagent is stable for the period shown on the bottle label if stored as directed.
储存条件 -20 °C
储存方法 Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
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Vascular Cell Adhesion Molecule 1 (VCAM1) 抗体
anti-Vascular Cell Adhesion Molecule 1 (VCAM1) antibody
抗原
Vascular Cell Adhesion Molecule 1 (VCAM1)
别名 fi76d06, wu:fi76d06, zgc:158875, VCAM1, CD106, INCAM-100, Vcam-1, VCAM1B
适用
其他选择 小鼠
宿主
其他选择 大鼠
克隆类型 (克隆位点)
单克隆 (M-K-2)
标记
其他选择 非结合性
应用范围
其他选择 流式细胞分析技术(FACS), 免疫组织化学(IHC), 免疫沉淀(IP)
Pubmed 2个引用可参考
规格 0.5 mg
发货至 中国 (更改)
产品细节Vascular Cell Adhesion Molecule 1 (VCAM1) 抗体
克隆位点 M-K-2
亚型 IgG1
产品特性 The antibody detects: CD106/VCAM-1 (approx. Mr 100 kDa)
The M/K-2 monoclonal antibody immunoprecipitates a peptide that gives a single band on SDS-PAGE gels with an apparent Mr of approx. 100 kDa under reducing conditions and 92 kDa under nonreducing conditions.
内毒素水平 Low Endotoxin
目标详细情况 Vascular Cell Adhesion Molecule 1 (VCAM1) 抗体
别名 CD106/VCAM-1
背景 VCAM-1 is an adhesion molecule and a major mediator of the inflammatory response. It is expressed on activated microvascular endothelial cells in response to signals arising from immune responses in infection, graft rejection, tumor recognition and killing. The complementary binding ligand for VCAM-1 is VLA-4/CD49d. In addition to VCAM-1, VLA-4 also recognizes the extracellular matrix molecule fibronectin. This pairing of VCAM-1 and VLA-4 is able to provide a second signal (i.e., non-antigen specific) for T cell stimulation, such as that seen in transplantation. The monoclonal antibody MK-2 has been used in transplant studies to suppress cardiac rejection and induce long-term cardiac graft survival. In addition to inflammatory responses, VCAM-1 has a significant role in hemopoiesis through its ability to retain lymphocyte and myeloid precursors on stromal cells in the marrow and lymphoid organs. CD106/VCAM-1 exists as an integral membrane protein.
使用细节 Vascular Cell Adhesion Molecule 1 (VCAM1) 抗体
应用备注 Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
样本量 1 mL
限制 仅限研究用
贮存及处理 Vascular Cell Adhesion Molecule 1 (VCAM1) 抗体
缓冲液 Product is supplied as 0.5 mg purified immunoglobulin in 1.0 mL of PBS.
储存液 Azide free
注意事项 Each reagent is stable for the period shown on the bottle label if stored as directed.
储存条件 -20 °C
储存方法 Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
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yb-0618R COX10细胞色素c氧化酶10抗体 浓度1mg/ml
yb-2546R CRTAMCRTAM抗体 浓度1mg/ml
yb-2468R MCP4单核细胞趋化蛋白4抗体 浓度1mg/ml
yb-2642R KIR2DL3NK细胞抑制性受体2DL3抗体 浓度1mg/ml
yb-3798R CRX1CRX抗体 浓度1mg/ml
yb-0648R CD8CD8抗体 浓度1mg/ml
yb-3089R phospho-CBL2 (Tyr731)磷酸化原癌蛋白CBL2抗体 浓度1mg/ml
yb-3090R phospho-CBL2 (Tyr774)磷酸化原癌蛋白CBL2抗体 浓度1mg/ml
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yb-3092R Phospho-cdc2 (Tyr15)磷酸化周期素依赖激酶2抗体 浓度1mg/ml
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yb-3093R Phospho-cdc25A (Thr506)磷酸化细胞分裂周期蛋白25抗体 浓度1mg/ml
yb-3094R Phospho-cdc25A (Ser76)磷酸化细胞分裂周期蛋白25抗体 浓度1mg/ml
yb-3095R Phospho-cdc25A (Ser178)磷酸化细胞分裂周期蛋白25抗体 浓度1mg/ml
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yb-8502R caspase-9 p10半胱胺酸蛋白酶蛋白9-p10抗体 浓度1mg/ml
yb-2663R CLEC5AC型凝集素结构域家族5成员A抗体 浓度1mg/ml
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yb-1390R Cdc6细胞分裂周期蛋白6抗体 浓度1mg/ml
yb-1392R CDC34细胞周期调控因子34 浓度1mg/ml
yb-1396R CEBP Beta转录调节因子C/EBP β抗体 浓度1mg/ml
yb-1397R CBPCREB结合蛋白抗体 浓度1mg/ml
yb-1601R CCL11嗜酸粒细胞趋化蛋白抗体 浓度1mg/ml
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Vascular Cell Adhesion Molecule 1 (VCAM1) 抗体
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